| Yazarlar |
Thu Thi Pham
|
|
Majid Monajjemi
|
|
Dung My Thi Dang
|
Dr. Öğr. Üyesi Fatemeh MOLLAAMIN
Kastamonu Üniversitesi |
|
Chien Mau Dang
|
| Özet |
| Cell membranes have unique features to store bio-energy in the physiology subjects. This work demonstrates a model of biological capacitors in the phospholipids bilayers membrane including DPPC, DOPG, DOPE, DOPS and DMPC structures. The electron densities profiles, electron localization function (ELF) and local information entropies have been used for studyng the interaction of G-proteins with phospholipid bilayers. The quantum and columbic blockade effects in different sizes and thicknesses of the membrane have also been specifically studied. It has been shown the quantum effect might appear in the small regions of the free spaces through membrane thickness due to the number and variant of phospholipids layer. In addition, based on Heisenberg rule, it has been exhibited the quantum tunneling effects are allowed the micro position while they are not allowed in other shapes of membrane capacitors. Due to the dynamical behavior of the bilayers in the membrane, their capacitances are not fixed which mean they are variable capacitors. Although the G protein successor does not interact to the phospholipid bilayers but stabilizes a true activated situation of the receptor, for stabilizing an activated conformational structure is tightly influenced through the lipidic situation in G proteins in viewpoint of capacitors model. Through an external field the G- protein trance membrane, charges exert forces that can influence the state of the cell membrane. Consequently the charge capacitive susceptibility could resonate with self-induction of helical coils in the (GTP) or (GDP) likes digital switches. These resonances are the main reason for any biological pulses in cell signaling cooperation. |
| Anahtar Kelimeler |
| Cell membrane capacitors | G-proteins | GDP | GTP | Lipid bilayers | Variable capacitors |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SCOPUS dergilerinde yayımlanan tam makale |
| Dergi Adı | Biointerface Research in Applied Chemistry |
| Dergi ISSN | 2069-5837 |
| Dergi Tarandığı Indeksler | SCOPUS |
| Makale Dili | İngilizce |
| Basım Tarihi | 04-2019 |
| Cilt No | 9 |
| Sayı | 2 |
| Sayfalar | 3874 / 3883 |
| Doi Numarası | 10.33263/BRIAC92.874883 |
| Atıf Sayıları | |
| WoS | 4 |
| SCOPUS | 1 |
