Comparing the Effects of Ginger and Glibenclamide on Dihydroxybenzoic Metabolites Produced in Stz-Induced Diabetic Rats
Yazarlar (1)
Dr. Öğr. Üyesi Fatemeh MOLLAAMIN Kastamonu Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | International Journal of Endocrinology and Metabolism (Q4) | ||
| Dergi ISSN | 1726-913X Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 10-2013 |
| Cilt / Sayı / Sayfa | 11 / 4 / – | DOI | 10.5812/ijem.10266 |
| Makale Linki | http://dx.doi.org/10.5812/ijem.10266 | ||
| UAK Araştırma Alanları |
Fiziksel Kimya
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| Özet |
| Background The aim of the present study was to investigate the effect of ginger and glibenclamide on oxidative stress markers. Oxidative stress is caused by an unbalance between a relative overload of oxidants and depletion of antioxidants, as implicated in the pathogenesis of several chronic diseases, including atherosclerosis and diabetes mellitus. Regarding the role of oxidative stress in the pathogenesis of diabetes mellitus, we investigated the effect of ginger and glibenclamide in diabetic rats induced bystreptozocin (STZ). Objectives This study assessed the effects of ginger and glibenclamide on dihydroxybenzoic acid metabolites in diabetic rats. Materials and Methods In this study 30 Wistar strain male rats were divided into five groups: Group 1: Normal control receiving normal saline (0.9 0/0), Group 2: control DMSO (Dimethyl sulfoxide) (as solvent of glibenclamide), Group 3: Diabetic control receiving … |
| Anahtar Kelimeler |
| Free radical | Ginger | Glibenclamide | STZ -induced diabetic rats |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 17 |
| Scopus | 20 |
| Google Scholar | 26 |