Bone therapy through drug delivery of chelated [bisphosphonate-metal ions] adsorbed on the surface of carbon nanotubes
Yazarlar (2)
Dr. Öğr. Üyesi Fatemeh MOLLAAMIN Kastamonu Üniversitesi, Türkiye
Prof. Dr. Majıd MONAJJEMI Islamic Azad University, Central Tehran Branch, İran
| Makale Türü |
Özgün Makale
(SCOPUS dergilerinde yayınlanan tam makale)
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| Dergi Adı | Revista Colombiana De Ciencias Quimico Farmaceuticas Colombia | ||
| Dergi ISSN | 0034-7418 Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCOPUS | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2024 |
| Cilt / Sayı / Sayfa | 52 / 2 / 741–765 | DOI | 10.15446/rcciquifa.v52n2.110734 |
| Makale Linki | https://search.proquest.com/openview/6583f55a02654d3c40db49953f48f4c4/1?pq-origsite=gscholar&cbl=2035763 | ||
| UAK Araştırma Alanları |
Fen Bilimleri ve Matematik
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| Özet |
| Aim To investigate asingle-walled carbon nanotube (SWCNT) joint to bisphosphonate agents of 5AEL, 5AFX, 4QPF, 3DYG, 2F92, 2I19 chelated to metal cations of Mg2+, Ca2+, Sr2+ due to the direct electron transfer principle which has been studied by density functional theory methods. Method It has been accomplished the B3LYP/6-311+ G (d, p)/LANL2DZ to estimate the susceptibility of SWCNT for adsorbing 5AEL, 5AFX, 4QPF, 3DYG, 2F92, 2I19 chelated to metal cations of Mg2+, Ca2+, Sr2+ through nuclear magnetic resonance and thermodynamic parameters. Results The data explained that the feasibility of using SWCNT and bisphosphonate agents becomes the norm in metal chelating of delivery system, which has been selected through several bisphosphonate agents of 5AEL, 5AFX, 4QPF, 3DYG, 2F92, and 2I19 using DFT method due to physico-chemical properties of NMR and IR methodologies. |
| Anahtar Kelimeler |
| (5,5) armchair SWCNT | metal chelating | protein-bisphosphonate |
| Atıf Sayıları | |
| Scopus | 1 |
| Google Scholar | 3 |