Monitoring of inflammatory blood biomarkers in foals with Rhodococcus Equi pneumonia during antimicrobial treatment
Yazarlar (7)
Doç. Dr. Ömer DENİZ Kastamonu Üniversitesi, Türkiye
Dr. Öğr. Üyesi Gencay Ekinci Erciyes Üniversitesi, Türkiye
Ali Cesur Onmaz Erciyes Üniversitesi, Türkiye
Fatih Mehmet Derelli İzmit Stud And Breeding Station Of Jockey Club Of Türkiye, Türkiye
Francesco Fazio Università Degli Studi Di Messina, İtalya
Francesca Aragona Università Degli Studi Di Messina, İtalya
Ren´E Van Den Hoven Universität Wien, Avusturya
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | Journal of Equine Veterinary Science (Q2) | ||
| Dergi ISSN | 0737-0806 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2024 |
| Cilt / Sayı / Sayfa | 138 / 1 / 105103–0 | DOI | 10.1016/j.jevs.2024.105103 |
| Makale Linki | http://dx.doi.org/10.1016/j.jevs.2024.105103 | ||
| UAK Araştırma Alanları |
Veteriner İç Hastalıkları
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| Özet |
| Rhodococcus equi (R. equi), a gram-positive facultative intracellular pathogen, is a common cause of pneumonia in foals and represents a major cause of disease and death. The aim of the present study was to investigate the time-depended changes in White Blood Cells (WBC), basophils (Baso), neutrophils (Neu), lymphocytes (Lymf), monocytes (Mon), eosinophils (Eos), platelet (PLT) counts, fibrinogen (Fbg) concentration, interferon (IFN-α, IFN-γ) and interleukins (IL-2 and IL-10) in foals with clinical R. equi pneumonia. The main treatment was with azithromycin-rifampicin for 14 days. Blood was sampled prior to, 7 and 14 days after starting therapy. Treatment was associated with significantly decreased counts of WBC, (25.6 ± 6.7 and 14.2 ± 2,7 × 103/ml), Neu (18.6 ±6.2 and 10.7 ± 3.1 × 103/ml), Mon (1.5 ± 0.5 and 0.9 ± 0.2 × 103/ml) and Fbg (539 ± 124 and 287 ± 26 g/dl) between day 0 and day 14. IL-2 and IL … |
| Anahtar Kelimeler |
| Azithromycin-rifampicin | Cytokines | Foal | Innate immunity | Pneumonia | Rhodococcus equi |
Science Direct
Monitoring of inflammatory blood biomarkers in foals with Rhodococcus Equi pneumonia during antimicrobial treatment
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 6 |
| Scopus | 8 |
| Google Scholar | 10 |