Evaluation of possible COVID-19 reinfection in children: A multicenter clinical study: COVID-19 reinfection in children
Yazarlar (14)
İrem Ceren Erbaş
Dokuz Eylül Üniversitesi, Türkiye
Yıldız Ekemen Keleş
Tepecik Training And Research Hospital, Türkiye
Dr. Öğr. Üyesi Emine Hafize Erdeniz Ondokuz Mayis Üniversitesi, Türkiye
Doç. Dr. Ayşe Yılmaz Kastamonu Üniversitesi, Türkiye
Doç. Dr. Edanur Yeşil T. C. Sağlık Bakanlığı, Mersin Devlet Hastanesi, Türkiye
Prof. Dr. Özlem Çakıcı Kocaeli Üniversitesi, Türkiye
Mehtap Akça
Mersin Üniversitesi, Türkiye
Nursel Kara Ulu
Gazi University, Faculty Of Medicine, Türkiye
Fatih Dinç Dokuz Eylül Üniversitesi, Türkiye
Dilek Yılmaz Çiftdoğan Tepecik Training And Research Hospital, Türkiye
Prof. Dr. Selim Öncel Kocaeli Üniversitesi, Türkiye
Necdet Kuyucu
Mersin Üniversitesi, Türkiye
Prof. Dr. Anıl Tapısız Gazi University, Faculty Of Medicine, Türkiye
Prof. Dr. Nurşen Belet Dokuz Eylül Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Archives de Pediatrie (Q3)
Dergi ISSN 0929-693X Wos Dergi Scopus Dergi
Makale Dili İngilizce Basım Tarihi 04-2023
Cilt / Sayı / Sayfa 30 / 3 / 187–191 DOI 10.1016/j.arcped.2023.01.008
Makale Linki https://www.ncbi.nlm.nih.gov/pmc/articles/9902289
UAK Araştırma Alanları
Sağlık Bilimleri
Özet
Background: Although it was originally unknown whether there would be cases of reinfection of coronavirus disease 2019 (COVID-19) as seen with other coronaviruses, cases of reinfection were reported from various regions recently. However, there is little information about reinfection in children. Methods: In this study, we aimed to investigate the incidence and clinical findings of reinfection in pediatric patients who had recovered from COVID-19. We retrospectively evaluated all patients under 18 years of age with COVID-19 infection from a total of eight healthcare facilities in Turkey, between March 2020 and July 2021. Possible reinfection was defined as a record of confirmed COVID-19 infection based on positive reverse transcription-polymerase chain reaction (RT-PCR) test results at least 3 months apart. Results: A possible reinfection was detected in 11 out of 8840 children, which yielded an incidence of 0.12%. The median duration between two episodes of COVID-19 was 196 (92–483) days. When initial and second episodes were compared, the rates of symptomatic and asymptomatic disease were similar for both, as was the severity of the disease (p = 1.000). Also, there was no significant difference in duration of symptoms (p = 0.498) or in hospitalization rates (p = 1.000). Only one patient died 15 days after PCR positivity, which resulted in a 9.1% mortality rate for cases of reinfection in pediatric patients. Conclusion: We observed that children with COVID-19 were less likely to be exposed to reinfection when compared with adults. Although the clinical spectrum of reinfection was mostly similar to the first episode, we reported death of a healthy child during the reinfection.
Anahtar Kelimeler
Children | COVID-19 | Pediatrics | Reinfection | SARS-CoV-2