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Effect of NLR, PLR, RDW and HRR in the Evaluation of the Prognosis of Children with Pneumonia: Case-Control Study  
Yazarlar
Doç. Dr. Emrah ÇIĞRI Doç. Dr. Emrah ÇIĞRI
Kastamonu Üniversitesi, Türkiye
Funda Çatan İnan
Kastamonu University, Turkey
Eren Yildiz
Kastamonu University, Turkey
Özet
Objective: Pneumonia is one of the leading causes of child death worldwide. In our study, it was aimed to investigate the effect of complete blood count (CBC) parameters in predicting the prognosis of children with pneumonia. Material and Methods: 162 pediatric patients diagnosed with pneumonia in our hospital was re-viewed retrospectively. Patients were divided into 3 groups: Those treated in intensive care unit (Group I: severe pneumonia, n=57), those treated in the ward (Group II: moderate pneumonia, n=56) and those who recovered with outpatient treatment (Group III: mild pneumonia, n=49) and the CBC parameters of the patients at the time of first admission were compared before receiving any treatment. Results: Red cell distribution width (RDW), neutrophil/lymphocyte ratio (NLR) and C-reactive protein (CRP) were significantly higher than patients in Group II and Group III, while hemoglobin/RDW ratio (HRR) was significantly lower (p<0.001) in Group I patients. In patients in Group I, RDW and NLR were positively correlated with CRP (r=0.637; p<0.001, r=0.705; p<0.001, respectively), while HRR was negatively correlated with CRP (r=0.562; p<0.001). RDW, NLR, CRP and the combination of these values were found to have high sensitivity (89.5%, 91.2%, 86.0% and 87.7%, respectively) and specificity (86.7%, 90.5%, 86.7% and 87.6%, respectively) in predicting the presence of severe pneumonia, and area under the curve values were 0.944, 0.945, 0.938 and 0.953, respectively. Conclusion: RDW, NLR, HRR and CRP are effective parameters in predicting prognosis in children diagnosed with pneumonia and have high sensitivity and specificity in predicting admission to intensive care unit.
Anahtar Kelimeler
Child | pneumonia | prognosis
Makale Türü Özgün Makale
Makale Alt Türü SCOPUS dergilerinde yayımlanan tam makale
Dergi Adı Turkiye Klinikleri Journal of Medical Sciences
Dergi ISSN 1300-0292
Makale Dili İngilizce
Basım Tarihi 12-2023
Cilt No 43
Sayı 4
Sayfalar 343 / 349
Doi Numarası 10.5336/medsci.2023-99086