Drug delivery using doping of boron nitride nanosensor towards releasing chloroquine drug in the cells: A promising method for overcoming viral disease
Yazarlar (2)
Dr. Öğr. Üyesi Fatemeh MOLLAAMIN Kastamonu Üniversitesi, Türkiye
Prof. Dr. Majıd MONAJJEMI Islamic Azad University, Central Tehran Branch, İran
Makale Türü Açık Erişim Özgün Makale (SCOPUS dergilerinde yayınlanan tam makale)
Dergi Adı Revista Colombiana De Ciencias Quimico Farmaceuticas Colombia
Dergi ISSN 0034-7418 Scopus Dergi
Dergi Tarandığı Indeksler SCOPUS
Makale Dili İngilizce Basım Tarihi 01-2024
Cilt / Sayı / Sayfa 53 / 2 / 430–454 DOI 10.15446/rcciquifa.v53n2.114450
Makale Linki https://search.proquest.com/openview/c5c6ad62d8eb13681a6589b075b4224b/1?pq-origsite=gscholar&cbl=2035763
UAK Araştırma Alanları
Fen Bilimleri ve Matematik
Özet
Introduction Chloroquine drug as the SARS-CoV-2’s primary protease which can prevent in vitro viral duplication of all diverse experiments to now. Chloroquine drug is an anti-viral drug enlarged by Pfizer which can operate as an orally effective 3C-like protease inhibitor. Materials and Methods In this work, chloroquine drug has been evaluated in forbiddance of coronavirus across trapping on the boron nitride nanocage (B4N10_NC) functionalized with some atoms as the drug delivery procedure owing to the direct electron transfer principle which can be illustrated by quantum mechanics method of density functional theory (DFT). Results and Discussion As a matter of fact, it was performed the theoretical method of the B3LYP/6-311+ G (d, p) to account the aptitude of B4N10_NC for grabbing Chloroquine drug via density of electronic states, nuclear quadrupole resonance, nuclear magnetic resonance, and …
Anahtar Kelimeler
administración de fármacos | Chloroquine | Cloroquina | cloroquina | COVID–19 | COVID–19 | COVID–19 | Drug delivery | Drug delivery | X–B4N10 (X=Al/C/Si) | X–B4N10 (X=Al/C/Si) | X–B4N10 (X=Al/C/Si)