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Toxic element (As, Cd, Pb and Hg) biodistribution and blood biomarkers in Barbaresca sheep raised in Sicily: One Health preliminary study    
Yazarlar
Doç. Dr. Elif DOĞAN
Kastamonu Üniversitesi, Türkiye
Francesco Fazio
Francesca Aragona
Vincenzo Nava
Salvatore De Caro
Alessandro Zumbo
Özet
The health of humans, animals and the environment is interconnected. Adopting a One Health approach means intervening promptly to prevent the main diseases that affect animal health to guarantee the safety of livestock production. Exposure to toxic trace elements in sheep can lead to increased accumulation in different biological substrate, developing both acute and chronic diseases in humans and livestock. The aim of this study was to evaluate the bioaccumulation of arsenic (As), cadmium (Cd), lead (Pb) and mercury (Hg) in Sicilian Barbaresca sheep using the following biological substrates: milk, blood and fleece. An inductively coupled plasma mass spectrometer (ICP-MS) was used for As, Cd and Pb, and a direct mercury analyser (DMA-80) was used for Hg determination. In addition, the role of the haematological parameters as possible indicators of different biodistribution was evaluated. A statistically significant value was observed from our analysed metals in the substrates: arsenic (p < 0.001), cadmium (p < 0.01), lead (p < 0.001) and mercury (p < 0.0001). The correlation analysis showed a relationship between milk and blood for arsenic (p < 0.0001) and lead (p < 0.0001), and no correlation for the metals was observed between milk/blood and the haematological parameters analysed for the low concentration observed in the present study comforting the final consumer.
Anahtar Kelimeler
Barbaresca sheep | Bioaccumulation | Blood biomarkers | Livestock | One Health | Toxic metals
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Environmental Science and Pollution Research
Dergi ISSN 0944-1344
Dergi Tarandığı Indeksler SSCI
Makale Dili İngilizce
Basım Tarihi 06-2024
Cilt No 31
Sayı 31
Sayfalar 43903 / 43912
Doi Numarası 10.1007/s11356-024-34060-9
Makale Linki http://dx.doi.org/10.1007/s11356-024-34060-9