Incorporation of Nanoalumina Improves Mechanical Properties and Osteogenesis of Hydroxyapatite Bioceramics
Yazarlar (12)
Hossein Tavassoli
Iran University Of Science And Technology, İran
Iran University Of Science And Technology, İran
Jafar Javadpour Iran University Of Science And Technology, İran
Mahdiar Taheri Iran University Of Science And Technology, İran
Morteza Mehrjou Pasteur Institute Of Iran, İran
Newsha Koushki Université Mcgill, Kanada
Dr. Öğr. Üyesi Farzin ARİANPOUR Kastamonu Üniversitesi, Türkiye
Mohammad Majidi Pasteur Institute Of Iran, İran
Jalal Izadi-Mobarakeh Pasteur Institute Of Iran, İran
Babak Negahdari
Tehran University Of Medical Sciences, İran
Tehran University Of Medical Sciences, İran
Peggy Chan
Swinburne University Of Technology, Avustralya
Swinburne University Of Technology, Avustralya
Majid Ebrahimi Warkiani University Of Technology Sydney, Avustralya
Shahin Bonakdar Pasteur Institute Of Iran, İran
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | ACS Biomaterials Science and Engineering (Q4) | ||
| Dergi ISSN | 2373-9878 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2018 |
| Cilt / Sayı / Sayfa | 4 / 4 / 1324–1336 | DOI | 10.1021/acsbiomaterials.7b00754 |
| Özet |
| A handful of work focused on improving the intrinsic low mechanical properties of hydroxyapatite (HA) by various reinforcing agents. However, the big challenge regarding improving mechanical properties is maintaining bioactivity. To address this issue, we report fabrication of apatite-based composites by incorporation of alumina nanoparticles (n-Al2O3). Although numerous studies have used micron or submicron alumina for reinforcing hydroxyapatite, only few reports are available about the use of n-Al2O3. In this study, spark plasma sintering (SPS) method was utilized to develop HA-nAl2O3 dense bodies. Compared to the conventional sintering, decomposition of HA and formation of calcium aluminates phases are restricted using SPS. Moreover, n-Al2O3 acts as a bioactive agent while its conventional form is an inert bioceramics. The addition of n-Al2O3 resulted in 40% improvement in hardness along with a … |
| Anahtar Kelimeler |
| adipose derived mesenchymal stem cells | alumina | hydroxyapatite | nanocomposite | osteoblast |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Scopus | 47 |
| Google Scholar | 52 |