Endoplasmic reticulum stress and associated apoptosis are linked with the pathogenesis of white striping in broiler breast muscles
Yazarlar (10)
Doç. Dr. Umaır Ahsan Burdur Mehmet Akif Ersoy Üniversitesi, Türkiye
Bülent Özsoy Aydın Adnan Menderes Üniversitesi, Türkiye
Gamze Sevri Ekren Aşıcı Aydın Adnan Menderes Üniversitesi, Türkiye
Doç. Dr. Musa TATAR Kastamonu Üniversitesi, Türkiye
Beyza Nur Özpilavcı
Erkmen Tuğrul Epikmen Aydın Adnan Menderes Üniversitesi, Türkiye
Şule Yurdagül Özsoy Aydın Adnan Menderes Üniversitesi, Türkiye
Ehsan Karimiyan Khamseh
Massimiliano Petracci
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Poultry Science (Q1)
Dergi ISSN 0032-5791 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 10-2024
Cilt / Sayı / Sayfa 103 / 10 / 104103–104103 DOI 10.1016/j.psj.2024.104103
Makale Linki http://dx.doi.org/10.1016/j.psj.2024.104103
Özet
White striping (WS) that appears as white stripes parallel to the muscle fibrils is an emerging growth-related abnormality of broiler breast meat. The pathomechanism of this defect has not been fully understood despite intensive studies over the past decade. In the present study, endoplasmic reticulum (ER) stress and its associated apoptotic pathways were investigated to elucidate the potential role of these pathways in the development of WS. To this end, a total of 60 Pectoralis major (Pm) muscle samples were collected from 55-d-old Ross 308 male broiler chickens according to the severity of gross WS lesions (normal, mild, and severe). Histopathological and molecular analyses were conducted to evaluate the lesions and genes involved in the ER stress and related apoptosis. All the Pm samples, both with and without macroscopic WS lesions, showed varying degrees of myodegenerative lesions. Molecular …
Anahtar Kelimeler