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Demirtas Two-Step Treatment Model in Hypofunctional-Obstructed Kidneys: An Extended Series and Long-Term Prospective Results   
Yazarlar
Ahdullah Demirtas
Abdullah Golbasi
Ahmet S. Guleser
Gokhan Sonmez
Turev Demirtas
Öğr. Gör. Ahmet GÜR Öğr. Gör. Ahmet GÜR
Kastamonu Üniversitesi
Evket T. Tombul
Özet
This study aimed to present the short- and long-term results of Demirtas two-step treatment model in patients with obstructed-hydronephrotic kidneys functioning below 10%, and before deciding on nephrectomy, to evaluate whether this method can contribute to the accurate assessment. This prospective study included patients with unilateral renal obstruction and renal parenchymal loss assessed by computed tomography and whose renal function was found to be below 10% in Tc-99m-dimercaptosuccinic acid. In the first step, percutaneous nephrostomy (PCN) was performed. Two weeks later, the second step was performed, in which patients were offered nephrectomy (if renal function was <10%) or etiology-based treatment (if renal function was ≥10%). Thirty-eight patients were included in the study, comprising 20 (52.6%) men and 18 (47.4%) women with a mean age of 51.3±16.8 years. Mean baseline renal function was 6.0%, which increased to 10.8% two weeks after PCN (p=0.001). Renal function increased to above 10% in 20 (52.6%) out of 38 patients. Of these, 17 patients underwent etiology-based treatment and baseline, two-week, and 12-month renal function levels were 7.0%, 17.5%, and 18.8%, respectively (p<0.001). Demirtas two-step treatment model introduced in the present study can be recommended as a standard treatment modality in unilaterally obstructed kidneys functioning below 10% ability.
Anahtar Kelimeler
hydronephrosis | kidney | non-function | obstruction | percutaneous nephrostomy
Makale Türü Özgün Makale
Makale Alt Türü ESCI dergilerinde yayımlanan tam makale
Dergi Adı CUREUS JOURNAL OF MEDICAL SCIENCE
Makale Dili İngilizce
Basım Tarihi 06-2022
Cilt No 14
Sayı 6
Doi Numarası 10.7759/cureus.26128