| Yazarlar |
G. Halac
Bezmiâlem Vakıf Üniversitesi, Turkey |
|
E. Kilic
Bezmiâlem Vakıf Üniversitesi, Turkey |
|
M. A. Cikrikcioglu
Bezmiâlem Vakıf Üniversitesi, Turkey |
|
K. Celik
Bezmiâlem Vakıf Üniversitesi, Turkey |
|
A. Toprak-Erek
Istanbul Medeniyet University, Turkey |
|
S. Keskin
Bezmiâlem Vakıf Üniversitesi, Turkey |
|
I. Gultepe
Bezmiâlem Vakıf Üniversitesi, Turkey |
|
R. S. Celik
Bezmiâlem Vakıf Üniversitesi, Turkey |
|
N. Ozaras
Bezmiâlem Vakıf Üniversitesi, Turkey |
Prof. Dr. Abdulkadir YILDIZ
Kastamonu Üniversitesi, Türkiye |
|
S. Aydin
Yedikule Chest Disease and Thorax Surgery Education and Research Hospital, Turkey |
|
O. Akan
SSK Okmeydani Training Hospital, Turkey |
|
C. Karatoprak
Bezmiâlem Vakıf Üniversitesi, Turkey |
|
Y. Sekin
Bezmiâlem Vakıf Üniversitesi, Turkey |
|
T. Asil
Bezmiâlem Vakıf Üniversitesi, Turkey |
| Özet |
| OBJECTIVE: The aim of this study was to assess the predisposition for atherosclerosis in patients with RLS through serum sLOX-1 (serum Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1) measurements. BACKGROUND: Recent epidemiological studies have suggested an association of RLS with certain chronic conditions such as diabetes mellitus (DM), obesity, hypertension (HT), and hyperlipidemia. LOX-1 is expressed in endothelial cells, macrophages, and in smooth muscle cells under the effect of proatherogenic conditions. METHODS: This study was a prospective, cross-sectional, case-controlled. We measured the serum sLOX-1 levels in 37 restless legs syndrome patients and 38 controls. RESULTS: Serum sLOX-1 level was significantly lower in the patient group. The two groups were similar in glucose, HbA1c, creatinine, LDL cholesterol, TG, HDL, total protein, albumin, AST, ALT, GGT, ALP, HGB, HCT, MCV, transferrin saturation rate (TSR), ferritin, CRP, TSH, FT4, FT3, B12, and folic acid levels. Also the two groups were similar with respect to age at menarche, number of previous births, number of abortions and/or curettage, total duration of breastfeeding, percentage of patients in menopause, and age at menopause. CONCLUSION: Our results may suggest a lower atherosclerotic risk among RLS patients as compared to the general population. |
| Anahtar Kelimeler |
| Atherosclerosis | Restless legs syndrome | SLOX-1 |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SCOPUS dergilerinde yayımlanan tam makale |
| Dergi Adı | Bratislava Medical Journal |
| Dergi ISSN | 0006-9248 |
| Makale Dili | İngilizce |
| Basım Tarihi | 01-2016 |
| Cilt No | 117 |
| Sayı | 6 |
| Sayfalar | 316 / 320 |
| Doi Numarası | 10.4149/BLL_2016_063 |
| Atıf Sayıları | |
| SCOPUS | 4 |
