Multidirectional research for the therapeutic potential of Phlomoides molucelloides (Bunge) Salmaki: LC-MS/MS, antioxidant, enzyme inhibition, and antiproliferative characteristics
Yazarlar (9)
Anfal Izaldeen Mutar Al Kateeb
Kastamonu Üniversitesi, Türkiye
Kastamonu Üniversitesi, Türkiye
Dr. Öğr. Üyesi Enis Fuat TÜFEKCİ Kastamonu Üniversitesi, Türkiye
Prof. Dr. Yasemin ÇELİK ALTUNOĞLU Kastamonu Üniversitesi, Türkiye
Prof. Dr. Mehmet Cengiz BALOĞLU Kastamonu Üniversitesi, Türkiye
Nilufar Nilofar Selçuk Üniversitesi, Türkiye
Evren Yıldıztugay Selçuk Üniversitesi, Türkiye
József Jekő University Of Nyíregyháza, Macaristan
Zoltán Cziáky University Of Nyíregyháza, Macaristan
Prof. Dr. Gökhan Zengin Selçuk Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Process Biochemistry (Q2) | ||
| Dergi ISSN | 1359-5113 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 08-2024 |
| Cilt / Sayı / Sayfa | 143 / 1 / 302–314 | DOI | 10.1016/j.procbio.2024.05.011 |
| Makale Linki | https://doi.org/10.1016/j.procbio.2024.05.011 | ||
| Özet |
| Medicinal plants offer natural cures and inspire modern medicine's development. This study examined the antioxidant, enzyme-inhibitory, and antiproliferative activities of various extracts obtained from aerial and root fragments of Phlomoides molucelloides (Bunge) Salmaki. The extracts' overall phenolics, flavonoids, and compounds were defined using colorimetric and LC-MS/MS analyses. The highest total phenolic and flavonoid content was measured in the methanol and infusion extracts of the aerial fragments, with 102.21 mg RE/g and 51.33 mg GAE/g, respectively. Most compounds were defined as flavonoids, predominantly as apigenin and quercetin glycosides. Methanol, 70 % methanol, and infusion extracts from aerial parts had the highest antioxidant activity determined by DPPH, ABTS, CUPRAC, FRAP, metal chelation, and phosphomolybdenum analyses. Moreover, the methanol extract of the roots … |
| Anahtar Kelimeler |
| Antioxidant | Antiproliferative | Enzyme inhibition | Flavonoids | Phlomoides molucelloides (Bunge) Salmaki |
Science Direct
Multidirectional research for the therapeutic potential of Phlomoides molucelloides (Bunge) Salmaki: LC-MS/MS, antioxidant, enzyme inhibition, and antiproliferative characteristics
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 4 |
| Scopus | 4 |
| Google Scholar | 4 |