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The effect of intravitreal dexamethasone implant on central foveal thickness and choroidal thickness in retinal vein occlusion     
Yazarlar
Özgür Eroğul
Afyonkarahisar Sağlık Bilimleri Üniversitesi, Türkiye
Dr. Öğr. Üyesi Zübeyir YOZGAT Dr. Öğr. Üyesi Zübeyir YOZGAT
Kastamonu Üniversitesi, Türkiye
Dr. Öğr. Üyesi Mehmet Cem SABANER Dr. Öğr. Üyesi Mehmet Cem SABANER
Türkiye
Mustafa Doğan
Afyonkarahisar Sağlık Bilimleri Üniversitesi, Türkiye
Hamıdu Hamısı Gobeka
Afyonkarahisar Sağlık Bilimleri Üniversitesi, Türkiye
Özet
To investigate the effect of intravitreal dexamethasone implant on central foveal thickness and choroidal thickness in retinal vein occlusion. Clinical records and optical coherence tomography (OCT) scans of 41 naïve patients with retinal vein occlusion (RVO), who were initially treated with intravitreal dexamethasone (DEX) implant between 2016 and 2017 at Kocatepe University Faculty of Medicine, Department of Ophthalmology were investigated. Collected data included age and sex of the patients, crystalline lens status, baseline and final intraocular pressure, and OCT parameters including central foveal thickness and choroidal thickness. Twenty-two (53.7%) female and 19 (46.3%) male patients were enrolled in the study. There were 30 phakic and 11 pseudophakic patients. The intraocular pressure increased significantly from 15.19 mmHg to 17.8 mmHg (P = 0.005), and cataract extraction was performed in two patients who developed cataract after the treatment. There was a significant decrease in the central foveal thickness from 556 μm to 288 μm (P < 0.001). In addition, although there was no statistically significant change in choroidal thickness in the patients with branched retinal vein occlusion (P = 0.423), the patients with central retinal vein occlusion had statistically significant decrease in choroidal thickness measurements (P = 0.049). Therapeutic effect of the DEX implant not only influences retinal layer. Its influence may also extend further to the choroid layer, thereby leading to decrease in the choroidal thickness. Our results were mostly similar to the results of studies in literature which investigated the effects of the DEX implant therapy on the choroidal thickness of the patients with RVO.
Anahtar Kelimeler
Central foveal thickness | choroidal thickness | intravitreal dexamethasone implant | retinal vein occlusion
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı NIGERIAN JOURNAL OF CLINICAL PRACTICE
Dergi ISSN 1119-3077
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q4
Makale Dili İngilizce
Basım Tarihi 01-2021
Cilt No 24
Sayı 1
Sayfalar 121 / 126
Doi Numarası 10.4103/njcp.njcp_87_20
Makale Linki http://dx.doi.org/10.4103/njcp.njcp_87_20