| Yazarlar |
Dr. Öğr. Üyesi Mehmet Cem SABANER
Türkiye |
Mustafa Doğan
Afyonkarahisar Sağlık Bilimleri Üniversitesi, Türkiye |
|
Müberra Akdoğan
Afyonkarahisar Sağlık Bilimleri Üniversitesi, Türkiye |
|
Merve Şimşek
|
| Özet |
| To analyze the macular microvascular changes after panretinal photocoagulation (PRP) in patients with non-proliferative diabetic retinopathy (NPDR) and a large foveal avascular zone area, using optical coherence tomography angiography. Twenty-four eyes of 24 patients with peripheral ischemia, superficial foveal avascular zone (FAZ) area of larger than 0.350 mm, naive severe NPDR, and no clinically significant diabetic macular edema were included in this prospective study. The PRP was applied in 360-degree in a single session. The main outcome measures of the study were the difference in best-corrected visual acuity, central macular thickness, superficial and deep vascular plexus vessel densities, FAZ features, choroidal and outer retinal flow areas at the baseline versus at one and six months after PRP treatment. The study group consisted of 13 men and 11 women with a mean age of 68.11 ± 6.47 years. The baseline FAZ area was higher than at one and six months after PRP (0.416 ± 0.70, 0.399 ± 0.065 and 0.407 ± 0.066 mm; p = 0.001 and p = 0.002, respectively). At one month after PRP, deep capillary plexus vascular density in perifoveal region was statistically significantly lower than at six months after PRP and the baseline. (45.43 ± 4.27, 47.91 ± 4.26 and 49.04 ± 5.64 %; p = 0.001 and p = 0.001, respectively). The PRP effects retinal microvascular morphology in patients with NPDR and a large FAZ area. |
| Anahtar Kelimeler |
| Foveal avascular zone | Optical coherence tomography angiography | Panretinal photocoagulation | Retinal laser | Retinal vessel density |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY |
| Dergi ISSN | 1572-1000 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q3 |
| Makale Dili | İngilizce |
| Basım Tarihi | 06-2021 |
| Cilt No | 34 |
| Doi Numarası | 10.1016/j.pdpdt.2021.102298 |
| Makale Linki | http://dx.doi.org/10.1016/j.pdpdt.2021.102298 |
| Atıf Sayıları | |
| WoS | 7 |
