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Comparison of peripapillary vascular density as measured by optical coherence tomography angiography between various types of open-angle glaucoma    
Yazarlar
Merve Şimşek
Ayşe Yeşim Oral
Türkiye
Sibel İnan
Türkiye
Müberra Akdoğan
Türkiye
Dr. Öğr. Üyesi Mehmet Cem SABANER Dr. Öğr. Üyesi Mehmet Cem SABANER
Türkiye
Özet
The purpose of this study is to compare the peripapillary vascular density in patients with various types of open-angle glaucoma (primary open-angle glaucoma, pseudoexfoliative glaucoma and pigmentary glaucoma) with healthy subjects by optic coherence tomography angiography (OCTA). Twenty-seven eyes with diagnosed POAG, thirty-four eyes with diagnosed PXG, twenty eyes with diagnosed PG and thirty eyes of healthy individuals were included in our study. Peripapillary vessel density measurements were performed with all images; (AI-DD), intra-disc (ID-DD) and peripapillary (PP-DD); measurement of vascular density in the radial peripapillary capillary network was performed by OCTA. The Kruskal-Wallis test and post-hoc test were performed for statistical analysis. AI-DD was 50.76±2.07% in the healthy group, 47.12±2.57% in POAG, 39.71±6.64% in PXG, and 43.37±1.55% in PG. ID-DD was 50.49±3.74% in the healthy group, 49.51±6.83% in POAG, 38.42±13.46% in PXG, and 40.9±4.45% in PG. PP-DD was 51.26±3.12% in the healthy group, 50.13±3.04% in POAG, 42.31±7.31% in PXG, and 47.6±1.40% in PG. While it was found that all image and intra-disc vascular density measurements were statistically significantly lower in the PG and PXG group compared to the healthy group and the POAG (P<0.001), there was no significant difference between PXG and PG or between the control group and POAG. The lower radial peripapillary capillary density in PXG and PG compared to the POAG and healthy groups suggests that the blood flow around the optic disc is negatively affected in these patients.
Anahtar Kelimeler
Densité vasculaire péripapillaire radiale | Glaucome pigmentaire | Glaucome pseudoexfoliatif | OCTA | Pigmentary glaucoma | Pseudoexfoliative glaucoma | Radial peripapillary vascular density
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı JOURNAL FRANCAIS D OPHTALMOLOGIE
Dergi ISSN 0181-5512
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q4
Makale Dili İngilizce
Basım Tarihi 11-2023
Cilt No 46
Sayı 9
Sayfalar 1047 / 1054
Doi Numarası 10.1016/j.jfo.2023.03.023
Makale Linki http://dx.doi.org/10.1016/j.jfo.2023.03.023