Yazarlar |
Öğr. Gör. Dr. Ayşe ÖZDEMİR
Kastamonu Üniversitesi |
Pervin Karli
|
Salim Neselioglu
|
Özet |
To investigate the effect of thiol/disulfide homeostasis on the number of oocytes retrieved and metaphase 2 (M2) oocytes in patients undergoing fertilization. A prospective study of 94 patients who were admitted to the fertilization clinic was conducted. Serum samples were taken on the oocyte pick-up day and kept until the analysis. Thiol and disulfide were measured in order to evaluate the total thiol/disulfide. A statistically significant correlation was observed between disulfide and M2. This study provides an inexpensive and noninvasive method to measure oxidative stress, and suggests that there is a positive correlation between the number of M2 and disulfide, resulting in low-impact oxidative stress. |
Anahtar Kelimeler |
antioxidants | embryo | in vitro fertilization success | infertility | metaphase 2 | oocyte maturation | oxidative stress | pregnancy | serum | thiol | disulfide homeostasis |
Makale Türü | Özgün Makale |
Makale Alt Türü | ESCI dergilerinde yayımlanan tam makale |
Dergi Adı | FUTURE SCIENCE OA |
Dergi ISSN | 2056-5623 |
Makale Dili | İngilizce |
Basım Tarihi | 02-2020 |
Cilt No | 6 |
Sayı | 2 |
Doi Numarası | 10.2144/fsoa-2019-0132 |