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Does thiol/disulfide homeostasis affect the number of metaphase 2 oocyte in the treatment of in vitro fertilization?   
Yazarlar
Öğr. Gör. Dr. Ayşe ÖZDEMİR Öğr. Gör. Dr. Ayşe ÖZDEMİR
Kastamonu Üniversitesi
Pervin Karli
Salim Neselioglu
Özet
To investigate the effect of thiol/disulfide homeostasis on the number of oocytes retrieved and metaphase 2 (M2) oocytes in patients undergoing fertilization. A prospective study of 94 patients who were admitted to the fertilization clinic was conducted. Serum samples were taken on the oocyte pick-up day and kept until the analysis. Thiol and disulfide were measured in order to evaluate the total thiol/disulfide. A statistically significant correlation was observed between disulfide and M2. This study provides an inexpensive and noninvasive method to measure oxidative stress, and suggests that there is a positive correlation between the number of M2 and disulfide, resulting in low-impact oxidative stress.
Anahtar Kelimeler
antioxidants | embryo | in vitro fertilization success | infertility | metaphase 2 | oocyte maturation | oxidative stress | pregnancy | serum | thiol | disulfide homeostasis
Makale Türü Özgün Makale
Makale Alt Türü ESCI dergilerinde yayımlanan tam makale
Dergi Adı FUTURE SCIENCE OA
Dergi ISSN 2056-5623
Makale Dili İngilizce
Basım Tarihi 02-2020
Cilt No 6
Sayı 2
Doi Numarası 10.2144/fsoa-2019-0132