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Autologous skin graft, human dura mater and polypropylene mesh for the repair of ventral abdominal hernias: An experimental study   
Yazarlar
NA Kama
T Coskun
Dr. Öğr. Üyesi Hamza YAVUZ Dr. Öğr. Üyesi Hamza YAVUZ
Kastamonu Üniversitesi
M Doganay
E Reis
AZ Akat
Özet
To compare primary repair and grafting with one of two materials (one biological human dura mater, and one synthetic polypropylene mesh) or autologous skin, with primary repair alone in abdominal wall hernias in rats. Randomised experiment. Teaching hospital, Turkey. 72 male Wistar albino rats randomised into 4 groups of 18 rats each. These were further randomly divided into subgroups of 6 each that were killed on days 15, 30,and 45 postoperatively. Each test material was sutured to the abdominal wall by an onlay technique. Macroscopic and microscopic appearance, and strength of the abdominal wall. Macroscopically, dura mater grafts lost their original shape, but polypropylene and skin did not. When completely incorporated the skin grafts had developed a new fascia. Dura mater and polypropylene induced a pronounced inflammatory reaction at all three times postoperatively, and there were significantly more fibroblasts in the dura mater group on days 15 and 30, and in the skin graft group on day 45, than in the other groups (p < 0.05). Mechanical resistance and mean breaking strength were significantly greater in the skin graft group than in the other groups at all times tested (p < 0.05). Full thickness autologous skin grafts were stronger than both human dura mater and polypropylene mesh when used to reinforce primary repairs of abdominal wall hernias in rats.
Anahtar Kelimeler
autologous skin graft | dura mater | polypropylene | abdominal hernia
Makale Türü Özgün Makale
Makale Alt Türü ESCI dergilerinde yayımlanan tam makale
Dergi Adı EUROPEAN JOURNAL OF SURGERY
Dergi ISSN 1102-4151
Makale Dili İngilizce
Basım Tarihi 11-1999
Cilt No 165
Sayı 11
Sayfalar 1080 / 1085
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
WoS 17

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