Synthesis of new 5-iodoisatin derivatives: Predicting antioxidant inhibition activity with DFT studies
Yazarlar (1)
Prof. Dr. Muhammet Serdar ÇAVUŞ Kastamonu Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Journal of Molecular Structure (Q2)
Dergi ISSN 0022-2860 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 01-2025
Cilt / Sayı / Sayfa 1323 / 1 / 140826– DOI 10.1016/j.molstruc.2024.140826
Makale Linki http://dx.doi.org/10.1016/j.molstruc.2024.140826
UAK Araştırma Alanları
Atom, Molekül ve Lazer Fiziği
Özet
New 5-iodoisatin-aryl/alkyl/thiosemicarbazones (1–8) were synthesized from various isocyanates and 5-iodoisatin, and their structures were validated by spectroscopic and elemental analysis. The in vitro antioxidant activity of these compounds was tested using the DPPH free radical trapping method, yielding IC50 values ranging from 14.11 to 20.48 µM...
Anahtar Kelimeler
5-Iodoisatin | DFT | DPPH | HAT-SET reactions | Isocyanates | Thiosemicarbazones