Yazarlar |
Saadet Ilcın
Van Yüzüncü Yıl Üniversitesi, Turkey |
Sermın Algul
Van Yüzüncü Yıl Üniversitesi, Turkey |
Prof. Dr. Oğuz ÖZÇELİK
Kastamonu Üniversitesi, Türkiye |
Özet |
Depression is a widely observed psychiatric disorder that affects a quite large number of people all around the world. A major depressive disorder (MDD) is a multifactorial disease that IS associated with fluctuations in appetite, body weight, and energy situations in addition to serious mood problems. The aim of this review is to investigate a possible link between energy regulatory hormones of irisin and depressive disorders. Irisin is a hormone that plays a significant role in the regulation of lipid and glucose metabolism in skeletal muscle and adipose tissue. Irisin was also reported to play significant roles in the central nervous system. In the literature there are reports indicating a beneficial antidepressant role of irisin in MDD. It should be emphasised that the antidepressive effects of exercise could be the result of exercise-induced increased hormones of irisin. |
Anahtar Kelimeler |
FNDC5 | Irisin | Major depressive disorders | Obesity | Type 2 diabetes mellitus |
Makale Türü | Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri) |
Makale Alt Türü | SCOPUS dergilerinde yayımlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale |
Dergi Adı | Endokrynologia Polska |
Dergi ISSN | 0423-104X |
Makale Dili | İngilizce |
Basım Tarihi | 02-2022 |
Cilt No | 73 |
Sayı | 1 |
Sayfalar | 149 / 156 |
Doi Numarası | 10.5603/EP.a2021.0088 |