Role of contrast-enhanced breast magnetic resonance angiography in characterizing suspicious breast lesions and evaluating the relationship between prognostic factors
Yazarlar (6)
Doç. Dr. Ali Küpeli Trabzon Üniversitesi, Türkiye
Dr. Öğr. Üyesi Mehmet Koçak Türkiye
Doç. Dr. Gürkan Danışan İstanbul Medipol Üniversitesi, Türkiye
Furkan Ufuk
Pamukkale Üniversitesi, Türkiye
Pamukkale Üniversitesi, Türkiye
Furkan Kaya Afyonkarahisar Sağlık Bilimleri Üniversitesi, Türkiye
Doç. Dr. İsmail TAŞKENT Kastamonu Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(Diğer hakemli uluslarası dergilerde yayınlanan tam makale)
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| Dergi Adı | Journal of Surgery and Medicine | ||
| Dergi ISSN | 2602-2079 | ||
| Dergi Tarandığı Indeksler | Directory of Research Journals Indexing (DRJI) | ||
| Makale Dili | İngilizce | Basım Tarihi | 10-2019 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 25-10-2019 |
| Cilt / Sayı / Sayfa | 3 / 10 / 749–753 | DOI | 10.28982/josam.632294 |
| Makale Linki | https://doi.org/10.28982/josam.632294 | ||
| UAK Araştırma Alanları |
Radyoloji
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| Özet |
| Aim Breast cancer is the most commonly diagnosed cancer in women, and mammography and ultrasonography are the most frequently used diagnostic radiological methods. Although they are highly sensitive, their specificity is low. Angiography can be added as a standard breast magnetic resonance imaging (MRI) protocol to increase specificity. In this study, we aimed to investigate the effectiveness of breast vascularity by evaluating the presence of an adjacent vessel sign (AVS) and increased ipsilateral breast vascularity (IIBV) in characterizing breast masses. Methods 135 patients with a mean age of 47 years with radiologically or clinically suspicious breast masses underwent breast MRI before biopsy. The contrast-enhanced three-dimensional MR angiograms of the breasts were investigated for the presence of AVS and IIBV to characterize suspicious breast masses, and their correlation with histopathological prognostic factors were evaluated. Results Patients’ age, tumor size, and the presence of AVS and IIBV were significantly higher in malignant masses than in benign masses (P<0.001). The sensitivity, specificity, and accuracy of AVS and IIBV in predicting malignant masses from benign ones were 75%, 79.3%, 77% and 56.9%, 90.4% and 72.5%, respectively. In malignant masses, AVS and IIBV were both significantly associated with ER (P=0.005, P<0.001) and PR expression (P=0.003, P<0.001). We found no relationship between AVS, IIBV and C-ERBB2 expression (P=0.245 and P=0.085, respectively). Conclusion The presence of AVS and IIBV as determined from contrast-enhanced 3D MR angiograms may be reliable parameters … |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 1 |