Effect of Middle-age Plasma Therapy on Ileum Morphology, Immune Defense (IgA) and Cell Proliferation (Ki-67) of Female Aged Rats
Yazarlar (5)
Dr. Öğr. Üyesi Ender Deniz Asmaz Ankara Medipol Üniversitesi, Türkiye
Dr. Öğr. Üyesi Hikmet Taner Teker Ankara Medipol Üniversitesi, Türkiye
Dr. Öğr. Üyesi Zeynep Tuğçe Sertkaya Ankara Medipol Üniversitesi, Türkiye
Taha Ceylani Muş Alparslan Üniversitesi, Türkiye
Arş. Gör. Dr. Aysun İNAN GENÇ Kastamonu Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
|
||
| Dergi Adı | Histochemistry and Cell Biology (Q2) | ||
| Dergi ISSN | 0948-6143 Dergi Bilgileri (2025) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2025 |
| Kabul Tarihi | 21-11-2024 | Yayınlanma Tarihi | 17-12-2024 |
| Cilt / Sayı / Sayfa | 163 / 1 / 17– | DOI | 10.1007/s00418-024-02344-3 |
| Makale Linki | https://doi.org/10.1007/s00418-024-02344-3 | ||
| UAK Araştırma Alanları |
Biyokimya
Hücre Biyolojisi
|
||
| Özet |
| Blood plasma therapy, a new treatment method to eliminate the damage and deterioration caused by aging in many organ systems, has attracted increasing attention. The digestive tract, which cooperates with many different systems, has strong effects on our health. In the present study, the effects of plasma therapy on the ileum of elderly rats were investigated. Wistar rats (n = 7; 12–15 months old) were given pooled plasma collected from middle-age rats (6 months, n =28) (for 30 days, 0.3 ml daily, intravenously into the tail vein). At the end of the experiment, villus height, crypt depth, total mucosal thickness and surface absorption area were evaluated. In addition, the effects of IgA, which plays a role in the digestive system's defense against microorganisms, were examined. Both the cell proliferation intensity and proliferation index were evaluated in crypt cells. An increase was determined in all morphological … |
| Anahtar Kelimeler |
| Blood plasma treatment | IgA | Ileum | Ki-67 | Wistar rat |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 3 |
| Scopus | 4 |
| Google Scholar | 4 |