ROS in Apoptosis of Cancer Cells (Handbook of Oxidative Stress in Cancer: Mechanistic Aspects)
Yazarlar (1)
Doç. Dr. Ayşe GÜNEŞ BAYIR Kastamonu Üniversitesi, Türkiye
| Bölüm Adı | ROS in Apoptosis of Cancer Cells | ||
| Kitap Adı | Handbook of Oxidative Stress in Cancer: Mechanistic Aspects | ||
| Bölüm Sayfaları | 503-515 | ||
| Kitap Türü | Kitap Bölümü | ||
| Kitap Alt Türü | Alanında uluslararası yayınlanan kitap bölümü | ||
| Kitap Niteliği | Scopus indeksinde taranan bilimsel kitap | ||
| Kitap Dili | İngilizce | Basım Tarihi | 01-2021 |
| DOI Numarası | 10.1007/978-981-15-9411-3_41.pdf | ISBN | 978-981-15-4501-6 |
| Basıldığı Ülke | Endonezya | Basıldığı Şehir | Singapur |
| Kitap Linki | https://www.springer.com/gp/book/9789811594106 | ||
| UAK Araştırma Alanları |
Veteriner Gıda Hijyeni ve Teknolojisi
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| Özet |
| Carcinogenesis is a complex and multistep process ending with metastasis. Mainly, gene and metabolic pathways include endogenous and signaling molecular pathways which cause a rise in cell proliferation and a decrease in cell death. Apoptosis is a programmed cell death which can happen with extracellular and intracellular signals. Generally, the extrinsic and the intrinsic pathways are known as the two apoptotic pathways. The excessive ROS production in cancer cells can stimulate the cell proliferation, the DNA mutations, and the formation of drug-resistant cells. It may also ensure a basis for the development of novel therapeutic strategies that take advantage of overgenerating ROS to destroy cancer cells. As the ROS-producing agents have toxic side effects and potential mutagenic impact, caution should be exercised during their use. In this chapter, focus will be on ROS generation, the relationship … |
| Anahtar Kelimeler |
| Apoptosis | Cancer cells | Carcinogenesis | Reactive oxygen species |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 7 |