Comprehensive approaches on chemical composition and biological properties of Daphne pontica L. extracts
Yazarlar (7)
Prof. Dr. Yasemin ÇELİK ALTUNOĞLU Kastamonu Üniversitesi, Türkiye
Öğr. Gör. Tevfik Hasan Can Kastamonu Üniversitesi, Türkiye
Dr. Öğr. Üyesi Enis Fuat TÜFEKCİ Kastamonu Üniversitesi, Türkiye
Doç. Dr. Bahattin Deniz ALTUNOĞLU Kastamonu Üniversitesi, Türkiye
Prof. Dr. Mehmet Cengiz BALOĞLU Kastamonu Üniversitesi, Türkiye
Eulogio J Llorent-Martínez Universidad De Jaén, İspanya
Prof. Dr. Gökhan Zengin Selçuk Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Plant Biosystems (Q2) | ||
| Dergi ISSN | 1126-3504 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2022 |
| Kabul Tarihi | 09-10-2020 | Yayınlanma Tarihi | 03-11-2020 |
| Cilt / Sayı / Sayfa | 156 / 1 / 116–129 | DOI | 10.1080/11263504.2020.1837282 |
| Makale Linki | https://www.tandfonline.com/doi/full/10.1080/11263504.2020.1837282 | ||
| Özet |
| The genus Daphne presents great interest as a valuable source of natural agents in traditional medicine of various countries, including Turkey. In the current work, we investigated the phytochemical composition and biological properties of Daphne pontica L. extracts. Methanol extracts of roots, stems and leaves were prepared. The chemical characterization was performed by HPLC-ESI-MSn, observing that flavonoids and phenolic acids were the main compounds. Biological properties were studied in terms of antimicrobial, DNA protection, anticancer, and enzyme inhibitory properties (cholinesterases, tyrosinase, amylase and glucosidase). Methanol extracts of roots, leaves, and stems of D. pontica had antimicrobial effects against a broad range of bacteria. In addition, methanol extract of roots of D. pontica exhibited a promising anticancer activity that was shown to be dose- and time-dependent for HeLa cells with … |
| Anahtar Kelimeler |
| anticancer | antimicrobial | Daphne pontica L | enzymes | phenolics |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 7 |
| Scopus | 7 |
| Google Scholar | 13 |