Integration of in vitro and in silico approaches to assess three Astragalus species from Turkey flora: A novel spotlight from lab bench to functional applications
Yazarlar (9)
Prof. Dr. Gökhan Zengin Selçuk Üniversitesi, Türkiye
Abdullahi Ibrahim Uba Kadir Has Üniversitesi, Türkiye
Arş. Gör. Mustafa ÖÇAL Kastamonu Üniversitesi, Türkiye
Majid Sharifi-Rad University Of Zabol, İran
Giovanni Caprioli Università Degli Studi Di Camerino, İtalya
Simone Angeloni Università Degli Studi Di Camerino, İtalya
Prof. Dr. Yasemin ÇELİK ALTUNOĞLU Kastamonu Üniversitesi, Türkiye
Prof. Dr. Mehmet Cengiz BALOĞLU Kastamonu Üniversitesi, Türkiye
Evren Yıldıztugay Selçuk Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Food Bioscience (Q1) | ||
| Dergi ISSN | 2212-4292 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 01-2022 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 01-10-2022 |
| Cilt / Sayı / Sayfa | 49 / 1 / 1–12 | DOI | 10.1016/j.fbio.2022.101858 |
| Makale Linki | http://dx.doi.org/10.1016/j.fbio.2022.101858 | ||
| Özet |
| Members of the genus Astragalus have a great interest as a source of natural bioactive compounds on a scientific platform. To provide multidirectional insights into three Astragalus species (A. setulosus, A. anthylloides, and A. ovalis), the current work focused on the chemical characterization and biological properties of their extracts (aerial parts and roots). The chemical characterization of the extracts was detected by HPLC-MS/MS analysis. The biological properties were evaluated by antioxidant, enzyme inhibitory, and cytotoxic parameters. Assays for radical quenching, reducing capacity, and metal chelation were also used to evaluate antioxidant properties. To test the enzyme inhibitory effects of the extracts, cholinesterases, tyrosinase, α-amylase, and α-glucosidase were utilized as target enzymes. Two cancer cell lines, (MCF-7 (human breast cancer cell line) and HeLa (Human cervix cancer cell line), were … |
| Anahtar Kelimeler |
| Astragalus | Bioactive agents | Cytotoxic effect | Molecular docking | Phenolics |
Science Direct
Integration of in vitro and in silico approaches to assess three Astragalus species from Turkey flora: A novel spotlight from lab bench to functional applications
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 24 |
| Scopus | 27 |
| Google Scholar | 32 |