Biogenic platinum nanoparticles using black cumin seed and their potential usage as antimicrobial and anticancer agent
 
Yazarlar (9)
Aysenur Aygun Dumlupinar Üniversitesi, Türkiye
Fulya Gülbagca Dumlupinar Üniversitesi, Türkiye
Lutfiye Yildiz Ozer Khalifa University Of Science And Technology, Birleşik Arap Emirlikleri
Buket Ustaoğlu
Kastamonu Üniversitesi, Türkiye
Prof. Dr. Yasemin ÇELİK ALTUNOĞLU Kastamonu Üniversitesi, Türkiye
Prof. Dr. Mehmet Cengiz BALOĞLU Kastamonu Üniversitesi, Türkiye
Mehmet Nuri Atalar Iğdır Üniversitesi, Türkiye
Prof. Dr. Mehmet Hakkı Alma Iğdır Üniversitesi, Türkiye
Prof. Dr. Fatih Şen Kütahya Dumlupınar Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Journal of Pharmaceutical and Biomedical Analysis (Q2)
Dergi ISSN 0731-7085 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 10-2019
Kabul Tarihi Yayınlanma Tarihi 01-02-2020
Cilt / Sayı / Sayfa 179 / 1 / 112961–0 DOI 10.1016/j.jpba.2019.112961
Makale Linki https://linkinghub.elsevier.com/retrieve/pii/S0731708519321375
Özet
Herein, the biogenic platinum nanoparticles (Pt NPs) were synthesized by using black cumin seed (Nigella sativa L.) extract as a reducing agent. The biogenic platinum nanoparticles synthesized by black cumin seed extract was characterized in detail by Transmission Electron Microscopy (TEM), UV–vis spectrophotometer, X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS). According to TEM analysis, Pt nanoparticles have spherical shapes and sizes between 1–6 nm. Moreover, the biogenic Pt NPs was assessed for its cytotoxicity effect on MDA-MB-231 breast and HeLa cervical cancer lines and their antibacterial effect against selected strains of gram-positive and negative bacteria. The cytotoxicity and bacterial tests showed the effectiveness of biogenic Pt nanoparticles. Dose-dependent toxicity effects were shown in the MDA-MB-231 breast and HeLa cervical cancer lines (IC50: 36.86 μg/mL and …
Anahtar Kelimeler
Antibacterial | Anticancer | Biogenic platinum nanoparticles | HeLa cervical cancer lines | MDA-MB-231 | Nigella sativa L.