| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Journal of Pharmaceutical and Biomedical Analysis (Q2) | ||
| Dergi ISSN | 0731-7085 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 10-2019 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 01-02-2020 |
| Cilt / Sayı / Sayfa | 179 / 1 / 112961–0 | DOI | 10.1016/j.jpba.2019.112961 |
| Makale Linki | https://linkinghub.elsevier.com/retrieve/pii/S0731708519321375 | ||
| Özet |
| Herein, the biogenic platinum nanoparticles (Pt NPs) were synthesized by using black cumin seed (Nigella sativa L.) extract as a reducing agent. The biogenic platinum nanoparticles synthesized by black cumin seed extract was characterized in detail by Transmission Electron Microscopy (TEM), UV–vis spectrophotometer, X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS). According to TEM analysis, Pt nanoparticles have spherical shapes and sizes between 1–6 nm. Moreover, the biogenic Pt NPs was assessed for its cytotoxicity effect on MDA-MB-231 breast and HeLa cervical cancer lines and their antibacterial effect against selected strains of gram-positive and negative bacteria. The cytotoxicity and bacterial tests showed the effectiveness of biogenic Pt nanoparticles. Dose-dependent toxicity effects were shown in the MDA-MB-231 breast and HeLa cervical cancer lines (IC50: 36.86 μg/mL and … |
| Anahtar Kelimeler |
| Antibacterial | Anticancer | Biogenic platinum nanoparticles | HeLa cervical cancer lines | MDA-MB-231 | Nigella sativa L. |
| Atıf Sayıları | |
| Web of Science | 119 |
| Scopus | 157 |
| Google Scholar | 206 |
| Dergi Adı | Journal of Pharmaceutical and Biomedical Analysis |
| Yayıncı | Elsevier B.V. |
| Açık Erişim | Hayır |
| ISSN | 0731-7085 |
| E-ISSN | 1873-264X |
| CiteScore | 6,4 |
| SJR | 0,628 |
| SNIP | 0,964 |