Anticancer and biological properties of leaf and flower extracts of Echinacea purpurea (L.) Moench
Yazarlar (8)
Khawla Omran Mohamed Sharif Kastamonu Üniversitesi, Türkiye
Dr. Öğr. Üyesi Enis Fuat TÜFEKCİ Kastamonu Üniversitesi, Türkiye
Buket Ustaoğlu
Kastamonu Üniversitesi, Türkiye
Kastamonu Üniversitesi, Türkiye
Prof. Dr. Yasemin ÇELİK ALTUNOĞLU Kastamonu Üniversitesi, Türkiye
Prof. Dr. Gökhan Zengin Selçuk Üniversitesi, Türkiye
E.J. Llorent-Martínez Universidad De Jaén, İspanya
Dr. Öğr. Üyesi Kerim GÜNEY Kastamonu Üniversitesi, Türkiye
Prof. Dr. Mehmet Cengiz BALOĞLU Kastamonu Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Food Bioscience (Q2) | ||
| Dergi ISSN | 2212-4292 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 03-2021 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 01-06-2021 |
| Cilt / Sayı / Sayfa | 41 / 1 / 101005–101005 | DOI | 10.1016/j.fbio.2021.101005 |
| Makale Linki | http://dx.doi.org/10.1016/j.fbio.2021.101005 | ||
| Özet |
| Echinacea purpurea (L.) Moench is an important medicinal herb; its roots, leaves and, flowers have been used by the food and pharmaceutical industries. In this study, DNA protection, antimicrobial, antioxidant-enzyme inhibition, and antiproliferative activities of water, methanol (MeOH), and ethyl acetate (EA) extracts of leaves and flowers of E. purpurea were evaluated. In addition, total phenolics and flavonoids, as well as individual compounds, were identified using colorimetric assays and HPLC-ion trap mass spectrometry, respectively. Chicoric acid and its isomer were the most abundant natural compounds, with concentrations similar to previous studies of E. purpurea. All extracts had antimicrobial activity against a broad range of bacteria, particularly Enterococcus faecalis. The antiproliferative activity of the extracts on the HeLa cells was shown. The lowest value of IC50 (73 μg/ml) came from the 24 h MeOH … |
| Anahtar Kelimeler |
| American coneflower | Chicoric acid | Echinacea purpurea (L.) Moench | HeLa cells | Medicinal herbs |
Science Direct
Anticancer and biological properties of leaf and flower extracts of Echinacea purpurea (L.) Moench
| Atıf Sayıları | |
| Web of Science | 29 |
| Scopus | 34 |
| Google Scholar | 42 |