Biological synthesis of silver nanoparticles using Rheum ribes and evaluation of their anticarcinogenic and antimicrobial potential: A novel approach in phytonanotechnology
 
Yazarlar (10)
Ayşenur Aygün
Dumlupinar Üniversitesi, Türkiye
Fulya Gülbağça
Dumlupinar Üniversitesi, Türkiye
Doç. Dr. Mehmet Salih Nas Iğdır Üniversitesi, Türkiye
Prof. Dr. Mehmet Hakkı Alma Iğdır Üniversitesi, Türkiye
Doç. Dr. Mehmet Harbi Çalımlı Iğdır Üniversitesi, Türkiye
Buket Ustaoğlu
Kastamonu Üniversitesi, Türkiye
Prof. Dr. Yasemin ÇELİK ALTUNOĞLU Kastamonu Üniversitesi, Türkiye
Prof. Dr. Mehmet Cengiz BALOĞLU Kastamonu Üniversitesi, Türkiye
Kemal Cellat
Dumlupinar Üniversitesi, Türkiye
Prof. Dr. Fatih Şen Kütahya Dumlupınar Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Journal of Pharmaceutical and Biomedical Analysis
Dergi ISSN 0731-7085 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 02-2020
Kabul Tarihi Yayınlanma Tarihi 01-02-2020
Cilt / Sayı / Sayfa 179 / 1 / 113012–0 DOI 10.1016/j.jpba.2019.113012
Makale Linki https://linkinghub.elsevier.com/retrieve/pii/S0731708519322629
Özet
This paper reports the anticarcinogenic and antimicrobial properties of silver nanoparticles (Ag NPs) obtained by green synthesis using the extract of Rheum ribes (R. ribes), a medicinal plant. For the synthesis of Ag NPs, the ethanolic extracts of R. ribes were used as a reducing as well as the stabilizing agent. For the characterization of Ag NPs, advanced analytical methods such as transmission electron microscopy (TEM), X-Ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD), and UV–vis spectrophotometry were performed. The synthesized Ag NPs obtained from R. ribes were evaluated as a cytotoxic agent against MDA-MB-231 breast carcinoma cell line. The IC50 values of the nanoparticles were ranged from 165 to 99 μg/mL against MDA-MB 231 cell line for 24 h and 48 h, respectively. The results show that the use of Ag NPs at low concentrations show the toxic effect in the cancer cells. In addition …
Anahtar Kelimeler
Ag nanoparticle | Anticancer | Antimicrobial | Characterization | Green synthesis