Syzgium coriaceum Bosser J. Guého—An endemic plant potentiates conventional antibiotics, inhibits clinical enzymes and induces apoptosis in breast cancer cells
Yazarlar (9)
Mohamad Fawzi Mahomoodally University Of Mauritius, Mauritius
Asli Ugurlu Kastamonu Üniversitesi, Türkiye
Eulogio J. Llorent-Martínez Universidad De Jaén, İspanya
Meenathee Nagamootoo University Of Mauritius, Mauritius
Marie Carene Nancy Picot-Allain University Of Mauritius, Mauritius
Prof. Dr. Mehmet Cengiz BALOĞLU Kastamonu Üniversitesi, Türkiye
Prof. Dr. Yasemin ÇELİK ALTUNOĞLU Kastamonu Üniversitesi, Türkiye
Muzzammil Hosenally University Of Mauritius, Mauritius
Gokhan Zengin Selçuk Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Industrial Crops and Products
Dergi ISSN 0926-6690 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 01-2020
Kabul Tarihi Yayınlanma Tarihi 01-01-2020
Cilt / Sayı / Sayfa 143 / 1 / 111948–0 DOI 10.1016/j.indcrop.2019.111948
Makale Linki https://linkinghub.elsevier.com/retrieve/pii/S0926669019309586
Özet
Syzygium species are renowned for being important reservoirs of phytochemicals with pharmaceutical and biomedical potential. However, no attempt has been made to delineate the pharmacological potential and phytochemical profile of Syzgium coriaceum Bosser & J. Guého, an endemic plant to Mauritius. The present study aimed to determine the antibacterial, antioxidant, cytotoxicity, enzyme inhibitory and phytochemical profile of the ethyl acetate and methanol extracts of S. coriaceum. Preliminary qualitative phytochemical study of the extracts showed the presence of phenol, tannins, and alkaloids. Chemical characterisation showed the presence of derivatives of tannins, gallic acids, quercetin, and kaempferol. Potentiating activity between S. coriaceum extracts and antibiotics (ampicillin and streptomycin) using the checkerboard method showed additive interaction. The extracts showed potent 2,2-diphenyl-1 …
Anahtar Kelimeler
Antioxidant | Apoptosis | Checkerboard | Cytotoxicity | Enzyme | Phytochemical