Synergistic and Antagonistic Effects of Phenylalanine and Various Antibiotics on the Growth of Pathogenic Bacteria
Yazarlar (10)
Prof. Dr. Fatih Şen Kütahya Dumlupınar Üniversitesi, Türkiye
Mohamed Abdulhamıd Ganım
Kastamonu Üniversitesi, Türkiye
Kastamonu Üniversitesi, Türkiye
Prof. Dr. Mehmet Cengiz BALOĞLU Kastamonu Üniversitesi, Türkiye
Ayşenur Aygün
Dumlupinar Üniversitesi, Türkiye
Dumlupinar Üniversitesi, Türkiye
Prof. Dr. Hakan Sezgin Sayiner Adıyaman Üniversitesi, Türkiye
Prof. Dr. Yasemin ÇELİK ALTUNOĞLU Kastamonu Üniversitesi, Türkiye
Prof. Dr. Fatma Kandemirli Kastamonu Üniversitesi, Türkiye
Buse Demirkan Dumlupinar Üniversitesi, Türkiye
Esra Kuyuldar Dumlupinar Üniversitesi, Türkiye
Ela Bulut Dumlupinar Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(ESCI dergilerinde yayınlanan tam makale)
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| Dergi Adı | Bionanoscience | ||
| Dergi ISSN | 2191-1630 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | Emerging Sources Citation Index | ||
| Makale Dili | İngilizce | Basım Tarihi | 06-2019 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 19-01-2019 |
| Cilt / Sayı / Sayfa | 9 / 2 / 446–452 | DOI | 10.1007/s12668-019-0597-9 |
| Makale Linki | http://link.springer.com/10.1007/s12668-019-0597-9 | ||
| Özet |
| Broad-spectrum antibiotics have been widely used in the treatment of many systemic and local infections in humans and animals. Herein, we aimed to determine the synergistic and antagonistic effects of phenylalanine with antibiotics cefoxitin, amoxicillin, vancomycin, lincomycin, and bacitracin against 14 pathogenic bacteria. The effect of antibiotics, either alone or in combination with this biomolecular liquid, was tested using the disk diffusion method against different bacteria. The addition of phenylalanine to antibiotic disks directly affected their antimicrobial activity. All the antibiotics used did not show any antimicrobial activity against Staphylococcus haemolyticus when used alone. However, in combination with phenylalanine, each antibiotic inhibited the growth of S. haemolyticus. The use of this biomolecular liquid together with amoxicillin and vancomycin also increased the antimicrobial activity against … |
| Anahtar Kelimeler |
| Antagonistic-synergetic effect | Pathogenic bacteria strains | Phenylalanine |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 7 |
| Scopus | 9 |
| Google Scholar | 11 |