Cytokine gene polymorphisms in Turkish patients with inflammatory bowel disease
Yazarlar (11)
Prof. Dr. Yasemin ÇELİK ALTUNOĞLU Ankara Üniversitesi, Türkiye
Ülkü Daǧli Turkiye Yuksek Ihtisas Hospital, Türkiye
Mesut Yalin Kiliç Turkiye Yuksek Ihtisas Hospital, Türkiye
Murat Törüner Ankara Üniversitesi, Türkiye
Senem Ceren Özen Ankara Üniversitesi, Türkiye
Muhip Özkan Ankara Üniversitesi, Türkiye
Irfan Soykan Ankara Üniversitesi, Türkiye
Hülya Çetinkaya Ankara Üniversitesi, Türkiye
Aysel Ülker Turkiye Yuksek Ihtisas Hospital, Türkiye
Ali Özden Ankara Üniversitesi, Türkiye
A. Mithat Bozdayi Ankara Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Scandinavian Journal of Gastroenterology | ||
| Dergi ISSN | 0036-5521 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2006 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 01-01-2006 |
| Cilt / Sayı / Sayfa | 41 / 5 / 559–565 | DOI | 10.1080/00365520500349523 |
| Makale Linki | http://www.tandfonline.com/doi/full/10.1080/00365520500349523 | ||
| Özet |
| Objective. Crohn's disease (CD) and ulcerative colitis (UC) are chronic inflammatory diseases of the bowel, the causes of which are not fully known. Ethnic differences in disease prevalence, familial aggregation of the disease and studies of twins provide the most important evidence to suggest that genetic factors play a role in the pathogenesis of inflammatory bowel disease (IBD). The aim of this study was to examine the allelic polymorphisms that can determine the immune response levels in tumor necrosis factor alpha (TNFα), interleukin-1β (IL-1B), interleukin-1 receptor antagonist ( IL-1RN) and interleukin-10 (IL-10) genes and to investigate their roles in the inflammatory pathway in IBD. Material and methods. The study included 120 patients with UC and 70 patients with CD who were diagnosed either endoscopically or histopathologically. The control group comprised 105 healthy individuals who stated that they … |
| Anahtar Kelimeler |
| Crohn's disease | Cytokine | Inflammatory bowel disease | Polymorphism | Ulcerative colitis |
Science Direct
Cytokine gene polymorphisms in Turkish patients with inflammatory bowel disease
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Scopus | 33 |
| Google Scholar | 55 |