NOD2 CARD15 NOD1 CARD4 and ICAM 1 Gene Polymorphisms in Turkish Patients with Inflammatory Bowel Disease
 
Yazarlar (11)
Senem Ceren Özen
Ankara Üniversitesi, Türkiye
Ülkü Daǧli
Turkiye Yuksek Ihtisas Hospital, Türkiye
Mesut Yalin Kiliç
Turkiye Yuksek Ihtisas Hospital, Türkiye
Murat Törüner Ankara Üniversitesi, Türkiye
Prof. Dr. Yasemin ÇELİK ALTUNOĞLU Ankara Üniversitesi, Türkiye
Muhip Özkan
Ankara Üniversitesi, Türkiye
Irfan Soykan
Ankara Üniversitesi, Türkiye
Hülya Çetinkaya Ankara Üniversitesi, Türkiye
Aysel Ülker
Turkiye Yuksek Ihtisas Hospital, Türkiye
Ali Özden
Ankara Üniversitesi, Türkiye
A. Mithat Bozdayi
Ankara Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Journal of Gastroenterology
Dergi ISSN 0944-1174 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 04-2006
Kabul Tarihi Yayınlanma Tarihi 02-06-2006
Cilt / Sayı / Sayfa 41 / 4 / 304–310 DOI 10.1007/s00535-005-1780-z
Makale Linki http://link.springer.com/10.1007/s00535-005-1780-z
UAK Araştırma Alanları
Biyoteknoloji
Özet
PurposeThe genetic susceptibility of people with certain NOD2/CARD15, NOD1/CARD4, and ICAM-1 gene variants to inflammatory bowel disease is still under investigation. The aim of this study was to investigate polymorphisms in the NOD2/CARD15 (R702W, G908R, and 3020insC), NOD1/CARD4 (E266K, D372N), and ICAM-1 (G241R, K469E) genes, which are known to be associated with inflammation, in Turkish patients with inflammatory bowel disease and healthy control groups.MethodsThe genotypes of 70 patients with endoscopically and histopathologically diagnosed Crohn's disease (38 men, 32 women; mean age, 38.8 ± 1.3), 120 patients with ulcerative colitis (67 men, 53 women; mean age, 41.7 ± 1.3) and 106 healthy control subjects (37 men, 69 women; mean age, 35.7 ± 1.4), who stated that they had never had any prior bowel disease history, were compared. A polymerase chain reaction …
Anahtar Kelimeler
Crohn's disease | ICAM | Inflammatory bowel disease | NOD/CARD | Ulcerative colitis
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Scopus 54
Google Scholar 77
NOD2 CARD15 NOD1 CARD4 and ICAM 1 Gene Polymorphisms in Turkish Patients with Inflammatory Bowel Disease

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