NOD2 CARD15 NOD1 CARD4 and ICAM 1 Gene Polymorphisms in Turkish Patients with Inflammatory Bowel Disease
Yazarlar (11)
Senem Ceren Özen Ankara Üniversitesi, Türkiye
Ülkü Daǧli Turkiye Yuksek Ihtisas Hospital, Türkiye
Mesut Yalin Kiliç Turkiye Yuksek Ihtisas Hospital, Türkiye
Murat Törüner Ankara Üniversitesi, Türkiye
Prof. Dr. Yasemin ÇELİK ALTUNOĞLU Ankara Üniversitesi, Türkiye
Muhip Özkan Ankara Üniversitesi, Türkiye
Irfan Soykan Ankara Üniversitesi, Türkiye
Hülya Çetinkaya Ankara Üniversitesi, Türkiye
Aysel Ülker Turkiye Yuksek Ihtisas Hospital, Türkiye
Ali Özden Ankara Üniversitesi, Türkiye
A. Mithat Bozdayi Ankara Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | Journal of Gastroenterology | ||
| Dergi ISSN | 0944-1174 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 04-2006 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 02-06-2006 |
| Cilt / Sayı / Sayfa | 41 / 4 / 304–310 | DOI | 10.1007/s00535-005-1780-z |
| Makale Linki | http://link.springer.com/10.1007/s00535-005-1780-z | ||
| Özet |
| PurposeThe genetic susceptibility of people with certain NOD2/CARD15, NOD1/CARD4, and ICAM-1 gene variants to inflammatory bowel disease is still under investigation. The aim of this study was to investigate polymorphisms in the NOD2/CARD15 (R702W, G908R, and 3020insC), NOD1/CARD4 (E266K, D372N), and ICAM-1 (G241R, K469E) genes, which are known to be associated with inflammation, in Turkish patients with inflammatory bowel disease and healthy control groups.MethodsThe genotypes of 70 patients with endoscopically and histopathologically diagnosed Crohn's disease (38 men, 32 women; mean age, 38.8 ± 1.3), 120 patients with ulcerative colitis (67 men, 53 women; mean age, 41.7 ± 1.3) and 106 healthy control subjects (37 men, 69 women; mean age, 35.7 ± 1.4), who stated that they had never had any prior bowel disease history, were compared. A polymerase chain reaction … |
| Anahtar Kelimeler |
| Crohn's disease | ICAM | Inflammatory bowel disease | NOD/CARD | Ulcerative colitis |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Scopus | 54 |
| Google Scholar | 77 |