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The effects of different mydriatics on intraocular pressure and central corneal thickness in new zealand white rabbits  
Yazarlar
Latif Emrah Yanmaz
Atatürk Üniversitesi, Turkey
Sitkican Okur
Atatürk Üniversitesi, Turkey
Uğur Ersöz
Atatürk Üniversitesi, Turkey
Mümin Gökhan Şenocak
Atatürk Üniversitesi, Turkey
Prof. Dr. Elif DOĞAN Prof. Dr. Elif DOĞAN
Kastamonu Üniversitesi, Türkiye
Zafer Okumuş
Atatürk Üniversitesi, Turkey
Özet
This study was aimed to compare the effect of 1% atropine, 1% cyclopentolate, 0.5% tropicamide, and 10% phenylephrine eye drops on intraocular pressure (IOP) and central corneal thickness (CCT) in New Zealand White rabbits. Adult male, eight, New Zealand White rabbits were randomly received each of four mydriatic eye drops separately on left eye at a one-week washout period. Each rabbit received all of five different treatments (sterile saline solution, four mydriatic drugs) on the left eye, whereas no measurements were performed on the right eyes during the experiment. The IOP and CCT recordings of rabbits were performed until the pupil returned to normal diameter. The mean CCT values of sterile saline, 1% atropine, 0.5% tropicamide, 1% cyclopentolate, and 10% phenylephrine were 370±15, 368±17, 372±15, 364±18, and 360±17 µm, respectively, and no statistically significant differences (P>0.05) were observed among groups. The mean IOP values of control (sterile saline), 1% atropine, 0.5% tropicamide, 1% cyclopentolate, and 10% phenylephrine as, 9.7±2.1, 10.4±1.8, 10.3±2.1, 11.0±2.1, and 10±1.8 mmHg, respectively, and these were not statistically significant among groups (P>0.05). In conclusion, topical 1% atropine, 0.5% tropicamide 1% cyclopentolate, and 10% phenylephrine do not have significantly effect on IOP and CCT in New Zealand white rabbits.
Anahtar Kelimeler
Central corneal thickness | Intraocular pressure | Mydriatic | New Zealand white rabbit | Tropicamide
Makale Türü Özgün Makale
Makale Alt Türü SCOPUS dergilerinde yayımlanan tam makale
Dergi Adı Kafkas Universitesi Veteriner Fakultesi Dergisi
Dergi ISSN 1300-6045
Makale Dili İngilizce
Basım Tarihi 01-2021
Cilt No 27
Sayı 4
Sayfalar 425 / 429
Doi Numarası 10.9775/kvfd.2021.25402