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Altered luteal expression patterns of genomic and non-genomic progesterone receptors in bitches at different reproductive states   
Yazarlar (7)
Eyyüp Hakan Uçar
Türkiye
Cevdet Peker
Türkiye
Mustafa Hitit
Kastamonu Üniversitesi, Türkiye
Mehmet Köse
Türkiye
Doç. Dr. Musa TATAR Doç. Dr. Musa TATAR
Kastamonu Üniversitesi, Türkiye
Faruk Bozkaya
Türkiye
Mehmet Osman Atlı
Türkiye
Devamını Göster
Özet
The binding of steroid hormones to their specific receptors is necessary to exert their effects on target cells. Progesterone (P4), a steroid hormone, carries out its effects through both genomic and non-genomic (the cell membrane-associated) receptors. This study aimed to ascertain luteal expression patterns of genomic and non-genomic progesterone receptors in bitches in physiological (early dioestrus and early pregnant) and pathological (pyometra) reproductive states. Luteal tissue was collected from the bitches at early dioestrus (ED, n = 5), early pregnant (EP, n = 5), and pyometra (PY, n = 5). The expression profiles of Steroidogenic Acute Regulator Protein (STAR), Progesterone Receptor (PGR), Membrane Progestin Receptors (PAQR5, PAQR7 and PAQR8), and Progesterone Membrane Components (PGMRC1 and PGMRC2) were examined at the mRNA levels using Real-Time Polymerase Chain Reaction …
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı Theriogenology
Dergi ISSN 0093-691X Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q1
Makale Dili Türkçe
Basım Tarihi 04-2024
Cilt No 218
Sayfalar 153 / 162
Doi Numarası 10.1016/j.theriogenology.2024.02.001
Makale Linki https://doi.org/10.1016/j.theriogenology.2024.02.001