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High‐Sensitive Cardiac Troponin I and Th1/Th2 Polarization in Queens With Pyometra       
Yazarlar (6)
Doç. Dr. Tarık ŞAFAK Doç. Dr. Tarık ŞAFAK
Kastamonu Üniversitesi, Türkiye
Nevzat Saat
Balıkesir Üniversitesi, Türkiye
Öznur Yılmaz Koç
Siirt Üniversitesi, Türkiye
Mert Turanlı
Türkiye
Aslıhan Ayalp
Ali Rışvanlı
Türkiye
Devamını Göster
Özet
Objectives: To determine T helper (Th)1 and Th2 cytokine polarization, as well as high-sensitive cardiac troponin I (hs-cTnI) levels, in cats with pyometra. Methods: We used 40 queens in the study. A total of 20 out of these 40 queens were diagnosed with the pyometra group (PYO) and the other 20 made up the healthy group (control; CTR). We measured concentrations of hs-cTnI, aspartate aminotransferase (AST), creatine kinase (CK) and l-lactate in queens from both groups. Additionally, we measured cytokine concentrations in all queens. Results: The hs-cTnI concentration in the PYO group (26.95 ± 5.08 ng/L) was significantly higher than that of the CTR group (7.00 ± 0.82 ng/L) (p < 0.000). Furthermore, the PYO group had a higher CK concentration (344.50 ± 39.63 U/L) than the CTR group (191.00 ± 15.44 U/L) (p = 0.002). The PYO group also demonstrated higher concentrations of TNF-α (9.77 ± 0.81 ng/mL), IFN-γ (25.37 ± 2.09 ng/mL), IL-2 (4.37 ± 0.39 ng/mL), IL-4 (245.64 ± 15.83 pg/mL), IL-5 (63.13 ± 1.65 pg/mL) and IL-10 (123.58 ± 4.30 ng/mL) compared to the CTR group (p < 0.000). Conclusions: Overall, it is suggested that changes in cytokine concentrations increase in queens with pyometra, potentially causing harm to the heart muscle. It is crucial to consider that the heart muscle may also be affected in queens with pyometra during the treatment process.
Anahtar Kelimeler
high-sensitive cardiac troponin I | pyometra | queen | Th1/Th2 cytokine polarization
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Veterinary Medicine and Science
Dergi ISSN 2053-1095 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q2
Makale Dili Türkçe
Basım Tarihi 01-2025
Cilt No 11
Sayı 1
Doi Numarası 10.1002/vms3.70125
Makale Linki https://doi.org/10.1002/vms3.70125
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Google Scholar 1
High‐Sensitive Cardiac Troponin I and Th1/Th2 Polarization in Queens With Pyometra

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