Non-peripheral and peripheral tetrasubstituted metallophthalocyanines having dichlorophenylthio groups as novel biological active materials for antioxidant, DNA cleavage ...
Yazarlar (4)
Büşra Çuhadar
Ayfer Kalkan Burat
Gülay Giray
Sadin Özdemir
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Polyhedron (Q1) | ||
| Dergi ISSN | 0277-5387 Dergi Bilgileri (2023) | ||
| Dergi Tarandığı Indeksler | 0277-5387 | ||
| Makale Dili | İngilizce | Basım Tarihi | 11-2023 |
| Cilt / Sayı / Sayfa | 244 / 0 / 116593–0 | DOI | – |
| Makale Linki | https://www.sciencedirect.com/science/article/pii/S0277538723003157 | ||
| UAK Araştırma Alanları |
Eğitim Bilimleri
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| Özet |
| We report the preperation of dichlorophenylthio substituted phthalonitrile (2) and its novel non-peripherally tetra sübstituted metallo phthalocyanines {Zn (3), Cu (4) and Mn (5)}. Characterization of newly synthesized compounds was performed by common spectroscopic techniques such as NMR, IR, UV–Vis and mass spectroscopies. The biological properties of the novel non-peripherally dichlorophenylthio substituted Pcs (3–5) and peripherally substituted derivatives (6, 7) were examined for the first time. Comparison of the biological properties of non-peripheral (α- substitution) substituted Pcs with those of peripheral derivatives (β-substution) was made. Among the studied compounds, 3 displayed the highest antioxidant activity as 99.42% at 200 mg/L. DNA cleavage activity of Pcs was also examined and all compounds were found to have DNA cleavage ability. Both peripherally and non-peripherally substituted … |
| Anahtar Kelimeler |
