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Non-peripheral and peripheral tetrasubstituted metallophthalocyanines having dichlorophenylthio groups as novel biological active materials for antioxidant, DNA cleavage ...  
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Büşra Çuhadar
Ayfer Kalkan Burat
Gülay Giray
Sadin Özdemir
Devamını Göster
Özet
We report the preperation of dichlorophenylthio substituted phthalonitrile (2) and its novel non-peripherally tetra sübstituted metallo phthalocyanines {Zn (3), Cu (4) and Mn (5)}. Characterization of newly synthesized compounds was performed by common spectroscopic techniques such as NMR, IR, UV--Vis and mass spectroscopies. The biological properties of the novel non-peripherally dichlorophenylthio substituted Pcs (3--5) and peripherally substituted derivatives (6, 7) were examined for the first time. Comparison of the biological properties of non-peripheral (α- substitution) substituted Pcs with those of peripheral derivatives (β-substution) was made. Among the studied compounds, 3 displayed the highest antioxidant activity as 99.42% at 200 mg/L. DNA cleavage activity of Pcs was also examined and all compounds were found to have DNA cleavage ability. Both peripherally and non-peripherally substituted ...
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Polyhedron
Dergi ISSN 0277-5387 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler 0277-5387
Dergi Grubu Q2
Makale Dili İngilizce
Basım Tarihi 11-2023
Cilt No 244
Sayfalar 116593 / 0
BM Sürdürülebilir Kalkınma Amaçları
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