Optimization of Bioactive Compound Extraction from Propolis by Reflux, Maceration and Ultrasound-assisted Methods and Characterization of the Extracts
Yazarlar (2)
Sevde Nur Şenol Yazkan
Kastamonu Üniversitesi, Türkiye
Kastamonu Üniversitesi, Türkiye
Prof. Dr. Müge HENDEK Kastamonu Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | Tarim Bilimleri Dergisi (Q3) | ||
| Dergi ISSN | 1300-7580 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2025 |
| Cilt / Sayı / Sayfa | 31 / 2 / 359–372 | DOI | 10.15832/ankutbd.1540221 |
| Makale Linki | https://dergipark.org.tr/en/pub/ankutbd | ||
| UAK Araştırma Alanları |
Gıda Teknolojileri
Fonksiyonel Gıdalar
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| Özet |
| The region, botanical origin, and bee species influence the raw propolis content and its bioactive properties. Additionally, the extraction methods, solvents, and various process parameters significantly affect the bioactive properties of propolis extract, which is consumed as a food supplement or pharmaceutical product. In this study, propolis with a chestnut botanical origin, obtained from the Black Sea region in Turkey, was used as the raw material. The process parameters of three basic extraction methods— maceration (M), reflux (R), and ultrasound-assisted (UA)—were optimised using response surface methodology. Antioxidant activity (AA) and total phenolic content (TPC) were used as response parameters. The optimised levels for M were 78.46% ethanol concentration and 71.05 hours for extraction time; for R, 80.64% ethanol concentration, 117.44 minutes for extraction time, and 38.38°C for temperature; and for UA, 82.49% ethanol concentration, 59.12 minutes for extraction time, and 40.53°C for temperature. The results were statistically validated using the t-test. The AA, TPC, and phenolic, volatile, and mineral contents were compared among the optimised chestnut propolis extracts. Chrysin, a flavone, and pinocembrin, a flavanone, along with ferulic and ellagic acid, among the phenolic acids, were identified as the most abundant phenolic compounds. Among the 11 elements, the highest macro elements were Na, K, and Ca, while the trace elements were Fe and Zn. The phenolic, volatile, and mineral compositions of the optimised propolis extracts exhibited heterogeneous distributions. However, fatty acids (e.g., 18:0, 18:1) were present … |
| Anahtar Kelimeler |
| Bee products | Bioactivity | Food supplement | Response surface methodology |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 1 |
| Scopus | 1 |
| Google Scholar | 2 |