Decoding Chemical Profiles, Biological Functions, and Medicinal Properties of Liquidambar orientalis Extracts Through Molecular Modeling and Bioinformatic Methods
Yazarlar (10)
Prof. Dr. Mehmet Cengiz BALOĞLU Kastamonu Üniversitesi, Türkiye
Lütfiye Yıldız Özer Hamad Bin Khalifa University, College Of Health And Life Sciences, Katar
Buket Pirci Kastamonu Üniversitesi, Türkiye
Prof. Dr. Yasemin ÇELİK ALTUNOĞLU Kastamonu Üniversitesi, Türkiye
Sanam Iram Soomro The Aga Khan University, Pakistan
Prof. Dr. Gökhan Zengin Selçuk Üniversitesi, Türkiye
Mehmet Veysi Çetiz Selçuk Üniversitesi, Türkiye
Simone Carradori University Of G. D'annunzio Chieti And Pescara, İtalya
Zoltán Cziáky University Of Nyíregyháza, Macaristan
József Jekő University Of Nyíregyháza, Macaristan
| Makale Türü |
Özgün Makale
(ESCI dergilerinde yayınlanan tam makale)
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| Dergi Adı | Food Frontiers | ||
| Dergi ISSN | 2643-8429 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | ESCI | ||
| Makale Dili | Türkçe | Basım Tarihi | 02-2025 |
| Cilt / Sayı / Sayfa | 6 / 3 / 1376–1408 | DOI | 10.1002/fft2.545 |
| Makale Linki | https://doi.org/10.1002/fft2.545 | ||
| Özet |
| Liquidambar orientalis, the Anatolian sweetgum tree, is a relict and endemic species in Southwestern Turkey, traditionally used for therapeutic purposes. Our study comprehensively evaluated the therapeutic potential of L. orientalis extracts from its aerial parts to maximize bioactive compound extraction using methanol, ethyl acetate, and water as solvents. The methanolic extract exhibited the highest phenolic (73.04 ± 3.94 mg gallic acid equivalent [GAE]/g) and flavonoid content (48.86 ± 0.76 mg rutin equivalent [RE]/g), demonstrating superior antioxidant activity in 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) (256.61 ± 1.70 mg Trolox equivalent [TE]/g), 2,2′‐azinobis‐(3‐ethylbenzothiazoline‐6‐sulfonic acid) (ABTS) (308.41 ± 3.14 mg TE/g), and cupric ion–reducing antioxidant capacity (CUPRAC) (411.13 ± 8.48 mg TE/g) assays. It also showed significant enzyme inhibition for acetylcholinesterase (4.43 ± 0.09 mg … |
| Anahtar Kelimeler |
| antioxidant and antibacterial synergy | Liquidambar orientalis | molecular docking analysis | multi-targeted therapies | phytochemical profiling | therapeutic targets |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 11 |
| Scopus | 10 |
| Google Scholar | 13 |