Serum soluble lectin-like oxidized low-density lipoprotein receptor-1 levels in patients with restless legs syndrome
Yazarlar (15)
G. Halac Bezmiâlem Vakıf Üniversitesi, Türkiye
E. Kilic Bezmiâlem Vakıf Üniversitesi, Türkiye
M. A. Cikrikcioglu Bezmiâlem Vakıf Üniversitesi, Türkiye
K. Celik Bezmiâlem Vakıf Üniversitesi, Türkiye
A. Toprak-Erek Istanbul Medeniyet University, Türkiye
S. Keskin Bezmiâlem Vakıf Üniversitesi, Türkiye
I. Gultepe Bezmiâlem Vakıf Üniversitesi, Türkiye
R. S. Celik Bezmiâlem Vakıf Üniversitesi, Türkiye
N. Ozaras Bezmiâlem Vakıf Üniversitesi, Türkiye
Prof. Dr. Abdulkadir YILDIZ Dicle Üniversitesi, Türkiye
S. Aydin Yedikule Chest Disease And Thorax Surgery Education And Research Hospital, Türkiye
O. Akan Ssk Okmeydani Training Hospital, Türkiye
C. Karatoprak Bezmiâlem Vakıf Üniversitesi, Türkiye
Y. Sekin Bezmiâlem Vakıf Üniversitesi, Türkiye
T. Asil Bezmiâlem Vakıf Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(SCOPUS dergilerinde yayınlanan tam makale)
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| Dergi Adı | Bratislava Medical Journal | ||
| Dergi ISSN | 0006-9248 Wos Dergi Scopus Dergi | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2016 |
| Cilt / Sayı / Sayfa | 117 / 6 / 316–320 | DOI | 10.4149/BLL_2016_063 |
| Makale Linki | http://www.scopus.com/inward/record.url?eid=2-s2.0-85014849674&partnerID=MN8TOARS | ||
| Özet |
| OBJECTIVE: The aim of this study was to assess the predisposition for atherosclerosis in patients with RLS through serum sLOX-1 (serum Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1) measurements. BACKGROUND: Recent epidemiological studies have suggested an association of RLS with certain chronic conditions such as diabetes mellitus (DM), obesity, hypertension (HT), and hyperlipidemia. LOX-1 is expressed in endothelial cells, macrophages, and in smooth muscle cells under the effect of proatherogenic conditions. METHODS: This study was a prospective, cross-sectional, case-controlled. We measured the serum sLOX-1 levels in 37 restless legs syndrome patients and 38 controls. RESULTS: Serum sLOX-1 level was significantly lower in the patient group. The two groups were similar in glucose, HbA1c, creatinine, LDL cholesterol, TG, HDL, total protein, albumin, AST, ALT, GGT, ALP, HGB, HCT, MCV, transferrin saturation rate (TSR), ferritin, CRP, TSH, FT4, FT3, B12, and folic acid levels. Also the two groups were similar with respect to age at menarche, number of previous births, number of abortions and/or curettage, total duration of breastfeeding, percentage of patients in menopause, and age at menopause. CONCLUSION: Our results may suggest a lower atherosclerotic risk among RLS patients as compared to the general population. |
| Anahtar Kelimeler |
| Atherosclerosis | Restless legs syndrome | SLOX-1 |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Scopus | 5 |