Yazarlar (6) |
![]() Kastamonu Üniversitesi, Türkiye |
![]() Kastamonu Üniversitesi, Türkiye |
![]() Kastamonu Üniversitesi, Türkiye |
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Özet |
Total knee arthroplasty (TKA) is a commonly performed surgical procedure for the treatment of advanced-stage knee osteoarthritis. This study aims to compare perioperative blood loss between tourniquet-assisted and tourniquet-free TKA using the reference change value (RCV), a personalized analytical tool that accounts for both biological and analytical variability. A retrospective analysis was conducted on 137 patients (tourniquet group (n = 68) and non-tourniquet group (n = 69) who underwent primary TKA. Hematological parameters-including red blood cell count (RBC), hemoglobin (HGB), and hematocrit (HCT)-were evaluated preoperatively, on the day of surgery, and on postoperative day one. Blood loss was assessed using both conventional statistical methods and RCV-based analysis. No statistically significant differences were observed between the two groups in terms of age and gender (p > 0.05). Although preoperative hemoglobin levels were significantly different between groups (p < 0.05), there were no significant intergroup differences in pre- or postoperative RBC and HCT values. Traditional statistical analysis showed no significant difference in blood loss (p > 0.05). However, RCV analysis revealed that while bleeding had stabilized by the first postoperative day in the non-tourniquet group, it remained significantly elevated in the tourniquet group. The findings suggest that RCV offers a more individualized and sensitive approach to assessing perioperative blood loss in TKA. Although conventional methods did not demonstrate significant differences, RCV analysis indicated a more rapid hemostatic response in the non-tourniquet group. Incorporating RCV into routine clinical practice may enhance patient-specific blood management and support earlier postoperative decision making. |
Anahtar Kelimeler |
Total knee arthroplasty | Perioperative blood loss | Reference change value | Tourniquet | Individualized hemostasis assessment |
Makale Türü | Özgün Makale |
Makale Alt Türü | ESCI dergilerinde yayımlanan tam makale |
Dergi Adı | ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY |
Dergi ISSN | 0936-8051 Wos Dergi Scopus Dergi |
Makale Dili | İngilizce |
Basım Tarihi | 06-2025 |
Cilt No | 145 |
Sayı | 1 |
Doi Numarası | 10.1007/s00402-025-05946-1 |