| Yazarlar (8) |
Özgür Yılmaz
T.C. Sağlık Bakanlığı, Türkiye |
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Ayşe Yılmaz
Kastamonu Üniversitesi, Türkiye |
Doç. Dr. Veysel Garani SOYLU
Kastamonu Üniversitesi, Türkiye |
Doç. Dr. Öztürk TAŞKIN
Kastamonu Üniversitesi, Türkiye |
|
Ufuk Demir
|
|
Gizem Kurada
Zonguldak Bülent Ecevit Üniversitesi, Türkiye |
Dr. Öğr. Üyesi Büşra TANYILDIZI KÜÇÜK
Kastamonu Üniversitesi, Türkiye |
Prof. Dr. Zahide DOĞANAY
Kastamonu Üniversitesi, Türkiye |
| Özet |
| Aims: In recent years, the rate of admission to intensive care in the elderly population has been increasing. We aimed to investigate the relationship between the serum creatinine/alanine transaminase ratio (sCr/ALT), which is thought to be a simpler method for predicting mortality in the elderly patient group instead of intensive care scoring systems that are difficult to calculate, and mortality. Methods: Medical records of patients treated in the intensive care unit due to acute ischemic stroke between January 2017 and October 2021 were evaluated. The study included 189 patients over the age of 85 who were diagnosed with cerebrovascular disease, had no known liver or kidney disease, and had a creatinine value of <1.5 mg/dl. APACHE II, SAPS II, and NIHSS scores calculated during admission to the intensive care unit were calculated from system data and patient records. Demographic data, additional diseases, hospital stay, laboratory values, sCr/ALT ratios and 28-day mortality status of the patients were recorded. Results: Among the 189 patients included in the study (66 males and 123 females), the 28-day mortality rate was 65.1% (n=123). The presence of coronary artery disease (p=0.044) was significantly higher in mortal cases. There were statistically significant differences in APACHE II score (p<0.001), SAPS II (p<0.001), AST (p=0.008), creatinine (p<0.001), sCr/ALT ratio (p<0.001), neutrophil/lymphocyte ratio (p=0.049), ferritin (p=0.003) and CRP (p=0.006) in mortal cases and non-mortals. In mortal cases, NIHSS severe (≥16) (p<0.001) percentage was significantly higher than in other patients. ALT (p<0.001), lymphocyte (p=0.009) and albumin (p<0.001) values were statistically significantly lower in mortal cases than in non-mortals. When we evaluated the 28-day mortality prediction performances of the variables, the sCr/ALT ratio was found to have 85.4% sensitivity and 84.8% specificity, the albumin value had 85.4% sensitivity and 60.6% specificity, and the APACHE II score had 61.8% sensitivity and 90.9% specificity. Conclusion: NIHSS, APACHE II and SAPS II are used as mortality and disease severity indicators in elderly intensive care patients with acute ischemic stroke. In comparison with these scoring systems, the sCr/ALT ratio appears to be a valuable predictor of mortality. We found that the sCr/ALT ratio, which is easily worked on and calculated in many centers, can better predict mortality in elderly patients with ischemic stroke. |
| Anahtar Kelimeler |
| Makale Türü |
Özgün Makale
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| Makale Alt Türü | Ulusal alan endekslerinde (TR Dizin, ULAKBİM) yayınlanan tam makale |
| Dergi Adı | Kastamonu Medical Journal (KASMEJ) |
| Dergi ISSN | 2757-9336 |
| Dergi Tarandığı Indeksler | TR DİZİN |
| Makale Dili | İngilizce |
| Basım Tarihi | 06-2025 |
| Cilt No | 5 |
| Sayı | 2 |
| Sayfalar | 123 / 127 |
| Doi Numarası | 10.51271/KMJ-0196 |
| Makale Linki | https://doi.org/10.51271/KMJ-0196 |
| Atıf Sayıları |
