| Yazarlar (9) |
Dr. Öğr. Üyesi Candemir ÖZCAN
Kastamonu Üniversitesi, Türkiye |
Arş. Gör. Serkan BOZACI
Kastamonu Üniversitesi, Türkiye |
Arş. Gör. Berrak Işık SOYTÜRK
Kastamonu Üniversitesi, Türkiye |
Doç. Dr. Kenan Çağrı TÜMER
Kastamonu Üniversitesi, Türkiye |
Dr. Öğr. Üyesi Ömer DENİZ
Kastamonu Üniversitesi, Türkiye |
Doç. Dr. Tarık ŞAFAK
Kastamonu Üniversitesi, Türkiye |
Dr. Öğr. Üyesi Ayşe Başak DELLALBAŞI
Kastamonu Üniversitesi, Türkiye |
Prof. Dr. Özgür KAYNAR
Kastamonu Üniversitesi, Türkiye |
Prof. Dr. Elif DOĞAN
Kastamonu Üniversitesi, Türkiye |
| Özet |
| The relationship between optic nerve sheath diameter (ONSD), an indicator of intracranial pressure (ICP), and intraocular pressure (IOP) is controversial. The two aims of this study were; first, to investigate the effect of cerebrospinal fluid (CSF) estradiol (E2) and progesterone (P4) levels on ONSD and second, to investigate the relationship between ONSD and IOP in female dogs. IOP measurements were performed using rebound tonometer, and transpalpebral ultrasonographic assessment of the ONSD was conducted. CSF samples were collected, and E2 and P4 levels were quantified using enzyme-linked immunosorbent assay (ELISA). Multiple regression analysis was conducted to assess the relationships among the variables. Multiple regression analyses on dogs found that the level of cerebrospinal fluid estradiol level (CSF-E2) significantly influenced left (L) ONSD (p = 0.0421, R² = 0.1551) and right (R) ONSD (p = 0.0216, R² = 0.1938). Systolic blood pressure (SBP) was a significant independent variable for left intraocular pressure (LIOP) (p = 0.0122, R² = 0.2261), while body weight was a significant predictor for right intraocular pressure (RIOP) (p = 0.0008, R² = 0.3679). This study revealed that CSF-E2 levels exert a significant influence on ONSD in dogs, whereas no direct association was observed between IOP and ONSD. These findings underscore the notion that ONSD is modulated not only by hemodynamic mechanisms but also by hormonal regulation. |
| Anahtar Kelimeler |
| Dog | Estradiol | Intraocular pressure | Optic nerve sheath diameter | Progesteron |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | Veterinary research communications |
| Dergi ISSN | 1573-7446 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | |
| Dergi Grubu | Q1 |
| Makale Dili | İngilizce |
| Basım Tarihi | 07-2025 |
| Cilt No | 49 |
| Sayfalar | 255 / 0 |
| Doi Numarası | 10.1007/s11259-025-10820-x |
| Atıf Sayıları |
