Cerebrospinal fluid estradiol fluctuations during the estrous cycle and their association with intraocular pressure and optic nerve sheath diameter in dogs: a first report.

ÖZCAN, Candemir; BOZACI, Serkan; DENİZ, Berrak Işık; TÜMER, Kenan Çağrı; DENİZ, Ömer; ŞAFAK, Tarık; DELLALBAŞI, Ayşe Başak; KAYNAR, Özgür; DOĞAN, Elif

doi:10.1007/s11259-025-10820-x

Cerebrospinal fluid estradiol fluctuations during the estrous cycle and their association with intraocular pressure and optic nerve sheath diameter in dogs: a first report.

Yazarlar (9)

Dr. Öğr. Üyesi Candemir ÖZCAN Kastamonu Üniversitesi, Türkiye

Arş. Gör. Serkan BOZACI Kastamonu Üniversitesi, Türkiye

Dr. Öğr. Üyesi Berrak Işık DENİZ Kastamonu Üniversitesi, Türkiye

Doç. Dr. Kenan Çağrı TÜMER Kastamonu Üniversitesi, Türkiye

Doç. Dr. Ömer DENİZ Kastamonu Üniversitesi, Türkiye

Doç. Dr. Tarık ŞAFAK Kastamonu Üniversitesi, Türkiye

Dr. Öğr. Üyesi Ayşe Başak DELLALBAŞI Kastamonu Üniversitesi, Türkiye

Prof. Dr. Özgür KAYNAR Kastamonu Üniversitesi, Türkiye

Prof. Dr. Elif DOĞAN Kastamonu Üniversitesi, Türkiye

Makale Türü	Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı	Veterinary Research Communications (Q2)
Dergi ISSN	0165-7380 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler	SCI-Expanded
Makale Dili	İngilizce	Basım Tarihi	07-2025
Cilt / Sayı / Sayfa	49 / 5 / 255–0	DOI	10.1007/s11259-025-10820-x
Makale Linki	https://doi.org/10.1007/s11259-025-10820-x
UAK Araştırma Alanları	Veteriner İç Hastalıkları

Özet

ObjectiveThe relationship between optic nerve sheath diameter (ONSD), an indicator of intracranial pressure (ICP), and intraocular pressure (IOP) is controversial. The two aims of this study were; first, to investigate the effect of cerebrospinal fluid (CSF) estradiol (E2) and progesterone (P4) levels on ONSD and second, to investigate the relationship between ONSD and IOP in female dogs.MethodsIOP measurements were performed using rebound tonometer, and transpalpebral ultrasonographic assessment of the ONSD was conducted. CSF samples were collected, and E2 and P4 levels were quantified using enzyme-linked immunosorbent assay (ELISA). Multiple regression analysis was conducted to assess the relationships among the variables.ResultsMultiple regression analyses on dogs found that the level of cerebrospinal fluid estradiol level (CSF-E2) significantly influenced left (L) ONSD (p = 0.0421, R² …

Anahtar Kelimeler

Dog | Estradiol | Intraocular pressure | Optic nerve sheath diameter | Progesteron

BM Sürdürülebilir Kalkınma Amaçları

Atıf Sayıları
Web of Science	1
Scopus	1
Google Scholar	1

Cerebrospinal fluid estradiol fluctuations during the estrous cycle and their association with intraocular pressure and optic nerve sheath diameter in dogs: a first report.

Dergi Adı	VETERINARY RESEARCH COMMUNICATIONS
Yayıncı	Springer Science and Business Media B.V.
Açık Erişim	Hayır
ISSN	0165-7380
E-ISSN	1573-7446
CiteScore	2,6
SJR	0,568
SNIP	0,887

Cerebrospinal fluid estradiol fluctuations during the estrous cycle and their association with intraocular pressure and optic nerve sheath diameter in dogs: a first report.

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