Consolidation of Ultrasound and Light: Silicon Phthalocyanine‐Based Sensitizer Therapeutic Agent for Synergetic Sonodynamic–Photodynamic Therapy of Breast Cancer
Yazarlar (11)
Hilal Çakmak
Sakarya University of Applied Sciences, Türkiye
Sakarya University of Applied Sciences, Türkiye
Aysegul Turkkol
Aydin Adnan Menderes University, Türkiye
Aydin Adnan Menderes University, Türkiye
Arş. Gör. Umut Kerem Kolac Aydin Adnan Menderes University, Türkiye
Doç. Dr. Göknur Yaşa Atmaca Yıldız Teknik Üniversitesi, Türkiye
Aleksey E. Kuznetsov Universidad Técnica Federico Santa María, Şili
Prof. Dr. Muhammet Serdar ÇAVUŞ Kastamonu Üniversitesi, Türkiye
Mustafa Z. Yıldız
Sakarya University of Applied Sciences, Türkiye
Sakarya University of Applied Sciences, Türkiye
Lukasz Sobotta
Poznan University of Medical Sciences, Polonya
Poznan University of Medical Sciences, Polonya
Prof. Dr. Mehmet Dincer Bilgin Aydin Adnan Menderes University, Türkiye
Prof. Dr. Ali Erdoğmuş Yıldız Teknik Üniversitesi, Türkiye
Prof. Dr. Emre Güzel Sakarya University of Applied Sciences, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | Advanced Therapeutics (Q2) | ||
| Dergi ISSN | 2366-3987 Dergi Bilgileri (2025) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 07-2025 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 06-07-2025 |
| Cilt / Sayı / Sayfa | 8 / 8 / – | DOI | 10.1002/adtp.202500053 |
| Makale Linki | https://doi.org/10.1002/adtp.202500053 | ||
| UAK Araştırma Alanları |
Atom, Molekül ve Lazer Fiziği
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| Özet |
| Sono‐photodynamic therapy (SPDT), a useful technique applied in combination with photodynamic therapy (PDT) and sonodynamic therapy (SDT), reduces potential side effects compared to monotherapy. This study reports the photochemical and sono‐photochemical properties and in vitro analysis of silicon (IV) phthalocyanine (SiPc), with a particular focus on its efficiency in singlet oxygen production. When photochemical investigations are conducted alone, the SiPc Φ∆ value is measured as 0.68; however, when light and ultrasound are combined, the value increased by 25% to 0.85 in sono‐photochemical studies. The Q‐band of the calculated SiPc UV–vis spectrum is found to be in very good agreement with the experimental data, with the computed oscillator strengths (the absorption intensities) for Q‐band being higher than for B‐band. Furthermore, the therapeutic effects of PDT and SPDT using SiPc are … |
| Anahtar Kelimeler |
| breast cancer | photodynamic therapy | phthalocyanine | sensitizer | silicon | sonodynamic therapy |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 1 |
| Scopus | 3 |
| Google Scholar | 3 |