Evaluation the Effects of Helichrysum plicatum Subsp. pseudoplicatum on an In-Vitro Wound Model Using Human Dermal Fibroblast Cells
Yazarlar (7)
Öğr. Gör. Abdulbaki AKPINAR Kastamonu Üniversitesi, Türkiye
Doç. Dr. Leyla Güven Atatürk Üniversitesi, Türkiye
Alper Kürşat Demirkaya
Türkiye
Türkiye
Prof. Dr. Gülşah Gündoğdu Pamukkale Üniversitesi, Türkiye
Dr. Öğr. Üyesi Kemal Alp Nalcı Türkiye
Prof. Dr. Ahmet Hacımüftüoğlu Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | The International Journal of Lower Extremity Wounds (Q3) | ||
| Dergi ISSN | 1534-7346 Dergi Bilgileri (2023) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 06-2023 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 14-05-2021 |
| Cilt / Sayı / Sayfa | 22 / 2 / 401–408 | DOI | 10.1177/15347346211016693 |
| Makale Linki | https://doi.org/10.1177/15347346211016693 | ||
| UAK Araştırma Alanları |
Analitik Kimya
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| Özet |
| Wound is tissue damage that occurs in the skin. Helichrysum species (Altınotu) are rich in phenolic compounds used in traditional medicine for wound healing. The main component in their flower head (capitulum) is phenolic compounds. The present study investigates the proliferative, oxidative stress, and wound healing properties of the methanolic extract of Helichrysum plicatum subsp. pseudoplicatum capitulum on a human dermal fibroblast (HDF) cell line in this study. H plicatum subsp. pseudoplicatum capitulums were collected in Erzurum, Turkey (altitude 1950 m), dried, pulverized, and extracted with methanol. Firstly, total phenolic contents were determined and secondly, the proliferative effect, oxidative stress activities, and wound healing effects on HDF cells were evaluated by the cell proliferation kit (XTT) test, total antioxidant status (TAS), and total oxidant status (TOS) commercial kits, and the scratch … |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 14 |