Predicting long-term cardiovascular outcomes of patients with acute myocardial infarction using soluble ST2
Yazarlar (8)
Prof. Dr. Mustafa Umut Somuncu Zonguldak Bülent Ecevit Üniversitesi, Türkiye
Belma Kalaycı
Zonguldak Bülent Ecevit Üniversitesi, Türkiye
Prof. Dr. Ahmet AVCI Zonguldak Bülent Ecevit Üniversitesi, Türkiye
Tunahan Akgün
Zonguldak Bülent Ecevit Üniversitesi, Türkiye
Hüseyin Karakurt
Ali Rıza Demir
Yalçın Avcı
Prof. Dr. Murat Can Zonguldak Bülent Ecevit Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (Uluslararası alan indekslerindeki dergilerde yayınlanan tam makale)
Dergi Adı Hormone Molecular Biology and Clinical Investigation
Dergi ISSN 1868-1883 Wos Dergi Scopus Dergi
Makale Dili İngilizce Basım Tarihi 02-2020
Cilt / Sayı / Sayfa 41 / 2 / – DOI 10.1515/hmbci-2019-0062
Makale Linki https://doi.org/10.1515/hmbci-2019-0062
Özet
BackgroundThe increase in soluble suppression of tumorigenicity 2 (sST2) both in the diagnosis and prognosis of heart failure is well established; however, existing data regarding sST2 values as the prognostic marker after myocardial infarction (MI) are limited and have been conflicting. This study aimed to assess the clinical significance of sST2 in predicting 1-year adverse cardiovascular (CV) events in MI patients.Materials and methodsIn this prospective study, 380 MI patients were included. Participants were grouped into low sST2 (n = 264, mean age: 60.0 ± 12.1 years) and high sST2 groups (n = 116, mean age: 60.5 ± 11.6 years), and all study populations were followed up for major adverse cardiovascular events (MACE) which are composed of CV mortality, target vessel revascularization (TVR), non-fatal reinfarction, stroke and heart failure.ResultsDuring a 12-month follow-up, 68 (17.8%) patients had MACE …
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