Growth Differentiation Factor 15 is Related with Left Ventricular Recovery in Patients with ST-Elevation Myocardial Infarction after Successful Reperfusion by Primary Percutaneous Intervention
Yazarlar (8)
Fatih Pasa Tatar
Belma Kalaycı
Türkiye
Prof. Dr. Ahmet AVCI Zonguldak Bülent Ecevit Üniversitesi, Türkiye
Begüm Uygur
Türkiye
Ali Riza Demir
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Acta cardiologica Sinica (Q3)
Dergi ISSN 1011-6842 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 07-2021
Cilt / Sayı / Sayfa – / 37 / 473–483 DOI 10.6515/ACS.202109_37(5).20210319A
Makale Linki https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414065/
Özet
Background The determinants of left ventricular (LV) recovery after successful revascularization in ST-elevation myocardial infarction (STEMI) patients are not clear. In addition, the relationship between growth differentiation factor15 (GDF-15) and left ventricular ejection fraction (LVEF) improvement is also unknown. This study hypothesizes that a low GDF-15 level would be associated with LVEF recovery. Methods One hundred and sixty-one STEMI patients were included in this study. Echocardiographic examinations were performed before and 12-18 weeks after discharge. The patients were divided into three groups according to the changes in LVEF as 62 patients with ≥ 10% change, 47 patients with 1-9% change, and 52 patients ≤ 0% change. LV recovery was defined as ≥ 10% LVEF improvement and the predictors of LV recovery were investigated. Moreover, two groups were created according to GDF-15 …
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