Total methylated arginine load as a risk parameter in subjects with masked hypertension
Yazarlar (7)
Muserref Hosaf
Sedat Abusoglu
Prof. Dr. Ahmet AVCI Zonguldak Bülent Ecevit Üniversitesi, Türkiye
Prof. Dr. Kenan Demir Selçuk Üniversitesi, Türkiye
Prof. Dr. Ali Ünlü Selçuk Üniversitesi, Türkiye
Doç. Dr. Duygu Eryavuz Selçuk Üniversitesi, Türkiye
Gulsum Abusoglu
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Clinical and Experimental Hypertension (Q4) | ||
| Dergi ISSN | 1064-1963 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 02-2020 |
| Cilt / Sayı / Sayfa | 42 / 2 / 126–130 | DOI | – |
| Makale Linki | https://www.tandfonline.com/doi/full/10.1080/10641963.2019.1583246 | ||
| Özet |
| Asymmetric dimethylarginine, symmetric dimethylarginine, and L-monomethylarginine are originated from the subsequent proteolytic catalysis of methylated arginine residues on different proteins and inhibit the endogenous nitric oxide generation. The changes in total methylarginine load (Asymmetric dimethylarginine plus symmetric dimethylarginine plus L-monomethylarginine) may contribute to hypertension. The aim of this study was to determine serum methylarginine concentrations in patients with masked hypertension and determine the association between these biomarkers and blood pressure measurements. Control group, masked hypertension and hypertension groups consisted of 40 subjects (11 males, 28 females, mean age 48.6 ± 13.1), 28 subjects (14 males, 14 females, mean age 50.9 ± 11.0) and 36 subjects (15 males, 21 females, mean age 54.4 ± 12.3 years), respectively (P= 0.149). Serum total … |
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