Synthesis, Characterization, Solvatochromic Properties, and Antimicrobial-radical Scavenging Activities of New Diazo Dyes Derived from Pyrazolo[1,5-a]pyrimidine
Yazarlar (4)
Prof. Dr. Nesrin ŞENER Kastamonu Üniversitesi, Türkiye
Selinay Erişkin
Pamukkale Üniversitesi, Türkiye
Pamukkale Üniversitesi, Türkiye
Prof. Dr. Serkan Yavuz Gazi Üniversitesi, Türkiye
Prof. Dr. İzzet ŞENER Kastamonu Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Journal of Heterocyclic Chemistry | ||
| Dergi ISSN | 0022-152X Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI | ||
| Makale Dili | İngilizce | Basım Tarihi | 11-2017 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 15-09-2017 |
| Cilt / Sayı / Sayfa | 54 / 6 / 3538–3548 | DOI | 10.1002/jhet.2977 |
| Makale Linki | http://doi.wiley.com/10.1002/jhet.2977 | ||
| UAK Araştırma Alanları |
Organik Kimya
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| Özet |
| 5‐Amino‐3‐methyl‐4‐phenylazo‐1H‐pyrazole and ethyl cyanoacetate reacted in solvent‐free media at 150°C to produce 7‐amino‐3‐phenylazo‐2‐methyl‐4H‐pyrazolo[1,5‐a]pyrimidine‐5‐one (3). A series of aromatic amines was coupled using this compound (3) and nitrous acid to produce new pyrazolo[1,5‐a] pyrimidine derivatives with two arylazo groups 4(a‐m). The structures of these dyes were determined via UV–vis, Fourier transform infrared, proton nuclear magnetic resonance, high‐resolution mass spectral data, and elemental analysis. After synthesis, the solvent and acid–base effects of the dyes were investigated within the UV–vis region. The antimicrobial properties of the dyes were also studied. All dyes exhibited activity against Gram‐positive and Gram‐negative bacteria, and even against fungi. The results were compared to conventional reference results from the antibiotics ciprofloxacin and … |
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| Atıf Sayıları | |
| Web of Science | 12 |
| Scopus | 16 |
| Google Scholar | 17 |