| Yazarlar (8) |
Murad Atmaca
Firat Üniversitesi Tip Fakültesi, Turkey |
|
Sevler Yildiz
Fethi Sekin City Hospital, Turkey |
Dr. Öğr. Üyesi İsmail TAŞKENT
Kastamonu Üniversitesi, Türkiye |
|
Muhammed Fatih Tabara
Firat Üniversitesi Tip Fakültesi, Turkey |
|
Mehmet Gurkan Gurok
Firat Üniversitesi Tip Fakültesi, Turkey |
|
Sevda Korkmaz
Firat Üniversitesi Tip Fakültesi, Turkey |
|
Osman Mermi
Firat Üniversitesi Tip Fakültesi, Turkey |
|
Hanefi Yildirim
Firat Üniversitesi Tip Fakültesi, Turkey |
| Özet |
| Purpose: The study aims to explore the relationship between orbitofrontal cortex (OFC) and thalamus volumes and metacognition in patients with obsessive-compulsive disorder (OCD). By analyzing structural MRI data and metacognitive measures, it investigates how brain volume variations correlate with dysfunctional beliefs and OCD symptoms. Method: The study consisted of 20 patients with OCD and 20 healthy controls. Yale-Brown Obsession Compulsion Scale (Y-BOCS), Metacognition Questionnaire-30 (MCQ-30), Hamilton Depression Scale (HAM-D), and Hamilton Anxiety Scale (HAM-A) were administered to OCD patients and healthy controls. They then underwent structural MRI scans to measure the volume of the OFC and thalamus. Finding: On both sides, OCD patients had smaller volumes of OFC than healthy control individuals, and their thalamic volumes were similar to those of the control participants. Furthermore, MCQ-30 scores showed a substantial negative correlation with left OFC volume. Conclusion: In conclusion, we suggest that dysfunctional metacognitive beliefs might be related to the occurrence of OCD, and these beliefs might be associated with the left side of OFC neuroanatomically. |
| Anahtar Kelimeler |
| metacognition | obsessive-compulsive disorder (OCD) | orbitofrontal cortex (OFC) | thalamus |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | Brain and Behavior |
| Dergi ISSN | 2162-3279 Wos Dergi Scopus Dergi |
| Dergi Grubu | Q2 |
| Makale Dili | İngilizce |
| Basım Tarihi | 08-2025 |
| Cilt No | 15 |
| Sayı | 8 |
| Doi Numarası | 10.1002/brb3.70716 |
| Atıf Sayıları |
